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4YN0

Crystal structure of APP E2 domain in complex with DR6 CRD domain

Summary for 4YN0
Entry DOI10.2210/pdb4yn0/pdb
DescriptorTumor necrosis factor receptor superfamily member 21, Amyloid beta A4 protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywordsalzheimer, neuron pruning, amyloid precursor protein, apoptosis-cell adhesion complex, apoptosis/cell adhesion
Biological sourceMus musculus (Mouse)
More
Total number of polymer chains2
Total formula weight48427.18
Authors
Xu, K.,Nikolov, D. (deposition date: 2015-03-08, release date: 2015-04-15, Last modification date: 2020-07-29)
Primary citationXu, K.,Olsen, O.,Tzvetkova-Robev, D.,Tessier-Lavigne, M.,Nikolov, D.B.
The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation.
Genes Dev., 29:785-790, 2015
Cited by
PubMed: 25838500
DOI: 10.1101/gad.257675.114
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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