4RSU
Crystal structure of the light and hvem complex
Summary for 4RSU
Entry DOI | 10.2210/pdb4rsu/pdb |
Related | 2AW2 4FHQ 4J6G |
Descriptor | Tumor necrosis factor ligand superfamily member 14, soluble form, Tumor necrosis factor receptor superfamily member 14, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | structural genomics, psi-biology, new york structural genomics, research consortium, nysgrc, immunity, n-glycosylation, membrane, secreted protein, cytokine, ifn, jelly-roll fold, protein structure initiative, atoms-to-animals: the immune function network, cysteine rich domain, signaling, cell membrane, secreted, immune system, new york structural genomics research consortium |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 197463.48 |
Authors | Liu, W.,Ramagoal, U.A.,Himmel, D.,Bonanno, J.B.,Nathenson, S.G.,Almo, S.C.,Atoms-to-Animals: The Immune Function Network (IFN),New York Structural Genomics Research Consortium (NYSGRC) (deposition date: 2014-11-11, release date: 2015-02-04, Last modification date: 2023-09-20) |
Primary citation | Liu, W.,Chou, T.F.,Garrett-Thomson, S.C.,Seo, G.Y.,Fedorov, E.,Ramagopal, U.A.,Bonanno, J.B.,Wang, Q.,Kim, K.,Garforth, S.J.,Kakugawa, K.,Cheroutre, H.,Kronenberg, M.,Almo, S.C. HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160. J.Exp.Med., 218:-, 2021 Cited by PubMed: 34709351DOI: 10.1084/jem.20211112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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