4RSU

Crystal structure of the light and hvem complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, G, H...	Tumor necrosis factor ligand superfamily member 14, soluble form	polymer	165	18188.5	6	UniProt (O43557) Pfam (PF00229) In PDB	Homo sapiens (human)	Herpes virus entry mediator ligand, HVEM-L, Herpesvirus entry mediator ligand, Tumor necrosis factor ligand superfamily member 14
2	D, E, F, J, K...	Tumor necrosis factor receptor superfamily member 14	polymer	134	14332.2	6	UniProt (Q92956) Pfam (PF00020) In PDB	Homo sapiens (human)	Herpes virus entry mediator A, Herpesvirus entry mediator A, HveA, Tumor necrosis factor receptor-like 2, TR2
3	G, H, I, K, L...	CHLORIDE ION	non-polymer		35.5	14	Chemie (CL)
4	G, H, I, B, C...	GLYCEROL	non-polymer		92.1	8	Chemie (GOL)
5	J, K, L, D, E	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)
6		water	water		18.0	223	Chemie (HOH)

Sequence modifications

A, B, C, G, H, I: 83 - 240 (UniProt: O43557)

PDB	External Database	Details
His 76	-	expression tag
His 77	-	expression tag
His 78	-	expression tag
His 79	-	expression tag
His 80	-	expression tag
His 81	-	expression tag
Gly 82	-	expression tag
Glu 214	Lys 214	conflict

D, E, F, J, K, L: 39 - 162 (UniProt: Q92956)

PDB	External Database	Details
Arg 37	-	expression tag
Ser 38	-	expression tag
Thr 163	-	expression tag
Gly 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag
His 168	-	expression tag
His 169	-	expression tag
His 170	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	195124.3
Non-Polymers*	Number of molecules	27
	Total formula weight	2339.1
All*	Total formula weight	197463.5

*Water molecules are not included.