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4E4D

Crystal structure of mouse RANKL-OPG complex

Summary for 4E4D
Entry DOI10.2210/pdb4e4d/pdb
Related1TNR 3ALQ 3K51 3ME2 3QBQ 3QO4
DescriptorTumor necrosis factor ligand superfamily member 11, soluble form, Tumor necrosis factor receptor superfamily member 11B, CHLORIDE ION, ... (4 entities in total)
Functional Keywordstnf-related activation-induced cytokine-receptor, cysteine-rich domain, jelly-roll fold, cytokine-signaling protein complex, cytokine/signaling protein
Biological sourceMus musculus (mouse)
More
Cellular locationIsoform 1: Cell membrane; Single-pass type II membrane protein. Isoform 2: Cell membrane; Single-pass type II membrane protein. Isoform 3: Cytoplasm. Tumor necrosis factor ligand superfamily member 11, soluble form: Secreted: O35235
Secreted: O08712
Total number of polymer chains2
Total formula weight37819.54
Authors
Nelson, C.A.,Fremont, D.H. (deposition date: 2012-03-12, release date: 2012-10-24, Last modification date: 2023-09-13)
Primary citationNelson, C.A.,Warren, J.T.,Wang, M.W.,Teitelbaum, S.L.,Fremont, D.H.
RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor.
Structure, 20:1971-1982, 2012
Cited by
PubMed: 23039992
DOI: 10.1016/j.str.2012.08.030
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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