4E4D
Crystal structure of mouse RANKL-OPG complex
Summary for 4E4D
Entry DOI | 10.2210/pdb4e4d/pdb |
Related | 1TNR 3ALQ 3K51 3ME2 3QBQ 3QO4 |
Descriptor | Tumor necrosis factor ligand superfamily member 11, soluble form, Tumor necrosis factor receptor superfamily member 11B, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | tnf-related activation-induced cytokine-receptor, cysteine-rich domain, jelly-roll fold, cytokine-signaling protein complex, cytokine/signaling protein |
Biological source | Mus musculus (mouse) More |
Cellular location | Isoform 1: Cell membrane; Single-pass type II membrane protein. Isoform 2: Cell membrane; Single-pass type II membrane protein. Isoform 3: Cytoplasm. Tumor necrosis factor ligand superfamily member 11, soluble form: Secreted: O35235 Secreted: O08712 |
Total number of polymer chains | 2 |
Total formula weight | 37819.54 |
Authors | Nelson, C.A.,Fremont, D.H. (deposition date: 2012-03-12, release date: 2012-10-24, Last modification date: 2023-09-13) |
Primary citation | Nelson, C.A.,Warren, J.T.,Wang, M.W.,Teitelbaum, S.L.,Fremont, D.H. RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor. Structure, 20:1971-1982, 2012 Cited by PubMed: 23039992DOI: 10.1016/j.str.2012.08.030 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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