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4E4D

Crystal structure of mouse RANKL-OPG complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(X)
Tumor necrosis factor ligand superfamily member 11, soluble formpolymer15517376.51UniProt (O35235)
Pfam (PF00229)
Mus musculus (mouse)Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE,
2B
(R)
Tumor necrosis factor receptor superfamily member 11Bpolymer18320372.21UniProt (O08712)
Pfam (PF00020)
Mus musculus (mouse)Osteoclastogenesis inhibitory factor, Osteoprotegerin
3C, D
(X)
CHLORIDE IONnon-polymer35.52Chemie (CL)
4E, F
(X, R)
waterwater18.093Chemie (HOH)
Sequence modifications
R: 1 - 176 (UniProt: O08712)
PDBExternal DatabaseDetails
Ala 177-expression tag
Ser 178-expression tag
Ser 179-expression tag
Val 180-expression tag
Leu 181-expression tag
Pro 182-expression tag
Arg 183-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight37748.6
Non-Polymers*Number of molecules2
Total formula weight70.9
All*Total formula weight37819.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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