4E4D

Crystal structure of mouse RANKL-OPG complex

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0005164	molecular_function	tumor necrosis factor receptor binding
X	0006955	biological_process	immune response
X	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL X 401

Chain	Residue
X	SER185
X	TRP186
X	LEU200
X	ASN202
X	GLY203
X	HOH526

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL X 402

Chain	Residue
X	HIS188
X	ASP189
X	ARG190

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Functional Information from PROSITE/UniProt

site_id	PS00652
Number of Residues	41
Details	TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Cpdhs..Ytdswhtsde.CvyCspvCkelqsvkqe..Cnrth..NRVC

Chain	Residue	Details
R	CYS44-CYS84

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	149
Details	Domain: {"description":"THD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01387","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	40
Details	Repeat: {"description":"TNFR-Cys 2"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	35
Details	Repeat: {"description":"TNFR-Cys 3"}

Chain

Residue

Details

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