Crystal Structure of DcR3-TL1A complex

Summary for 3K51

DescriptorTumor necrosis factor ligand superfamily member 15, secreted form, Decoy receptor 3 (3 entities in total)
Functional Keywordsdcr3, tl1a, tnf, tnfr, decoy receptor, immunity, cytokine, disulfide bond, glycoprotein, membrane, secreted, signal-anchor, transmembrane, apoptosis, receptor, immune system
Biological sourceHomo sapiens (human)
Cellular locationMembrane ; Single-pass type II membrane protein . Tumor necrosis factor ligand superfamily member 15, secreted form: Secreted O95150
Secreted O95407
Total number of polymer chains2
Total molecular weight40166.11
Zhan, C.,Patskovsky, Y.,Yan, Q.,Li, Z.,Ramagopal, U.A.,Nathenson, S.G.,Almo, S.C. (deposition date: 2009-10-06, release date: 2010-10-13, Last modification date: 2017-11-01)
Primary citation
Zhan, C.,Patskovsky, Y.,Yan, Q.,Li, Z.,Ramagopal, U.,Cheng, H.,Brenowitz, M.,Hui, X.,Nathenson, S.G.,Almo, S.C.
Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19:162-171, 2011
PubMed: 21300286 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2010.12.004
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.255140.7%6.7%23.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution