3K51

Crystal Structure of DcR3-TL1A complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Tumor necrosis factor ligand superfamily member 15, secreted form	polymer	184	20877.6	1	UniProt (O95150) Pfam (PF00229) In PDB	Homo sapiens (human)	Vascular endothelial cell growth inhibitor, TNF ligand-related molecule 1, Tumor necrosis factor ligand superfamily member 15, membrane form, Tumor necrosis factor ligand superfamily member 15, secreted form
2	B	Decoy receptor 3	polymer	176	19288.5	1	UniProt (O95407) Pfam (PF00020) In PDB	Homo sapiens (human)	Tumor necrosis factor receptor superfamily member 6B, Decoy receptor for Fas ligand, DcR3, M68
3		water	water		18.0	83	Chemie (HOH)

Sequence modifications

A: 5 - 184 (UniProt: O95150)

PDB	External Database	Details
Gly 1	-	expression tag
Ser 2	-	expression tag
His 3	-	expression tag
Met 4	-	expression tag
Ser 95	Cys 162	engineered mutation
Ser 135	Cys 202	engineered mutation

B: 30 - 195 (UniProt: O95407)

PDB	External Database	Details
Arg 28	-	expression tag
Ser 29	-	expression tag
Thr 196	-	expression tag
Gly 197	-	expression tag
His 198	-	expression tag
His 199	-	expression tag
His 200	-	expression tag
His 201	-	expression tag
His 202	-	expression tag
His 203	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	40166.1
All*	Total formula weight	40166.1

*Water molecules are not included.