3F7V
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![BU of 3f7v by Molmil](/molmil-images/mine/3f7v) | KcsA Potassium channel in the open-inactivated state with 23 A opening at T112 | Descriptor: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment Heavy chain, ... | Authors: | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | Deposit date: | 2008-11-10 | Release date: | 2010-05-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | KcsA Potassium channel in the open-inactivated state with 23 A opening at T112 TO BE PUBLISHED
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3HMX
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![BU of 3hmx by Molmil](/molmil-images/mine/3hmx) | Crystal structure of ustekinumab FAB/IL-12 complex | Descriptor: | Interleukin-12 subunit alpha, Interleukin-12 subunit beta, USTEKINUMAB FAB HEAVY CHAIN, ... | Authors: | Luo, J. | Deposit date: | 2009-05-29 | Release date: | 2010-06-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for the dual recognition of IL-12 and IL-23 by ustekinumab. J.Mol.Biol., 402, 2010
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3W11
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![BU of 3w11 by Molmil](/molmil-images/mine/3w11) | |
3FB7
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![BU of 3fb7 by Molmil](/molmil-images/mine/3fb7) | Open KcsA potassium channel in the presence of Rb+ ion | Descriptor: | RUBIDIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | Authors: | Cuello, L.G, Jogini, V, Cortes, D.M, Pan, A.C, Gagnon, D.H, Cordero-Morales, J.F, Chakrapani, S, Roux, B, Perozo, E. | Deposit date: | 2008-11-18 | Release date: | 2010-07-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Open KcsA potassium channel in the presence of Rb+ ion TO BE PUBLISHED
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3W13
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![BU of 3w13 by Molmil](/molmil-images/mine/3w13) | Insulin receptor ectodomain construct comprising domains L1-CR in complex with high-affinity insulin analogue [D-PRO-B26]-DTI-NH2, alphact peptide(693-719) and FAB 83-7 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ... | Authors: | Lawrence, M.C, Smith, B.J, Brzozowski, A.M. | Deposit date: | 2012-11-06 | Release date: | 2013-01-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (4.303 Å) | Cite: | How insulin engages its primary binding site on the insulin receptor Nature, 493, 2013
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3W12
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![BU of 3w12 by Molmil](/molmil-images/mine/3w12) | Insulin receptor ectodomain construct comprising domains L1-CR in complex with high-affinity insulin analogue [D-PRO-B26]-DTI-NH2, alpha-CT peptide(704-719) and FAB 83-7 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ... | Authors: | Lawrence, M.C, Smith, B.J, Brzozowsk, A.M. | Deposit date: | 2012-11-06 | Release date: | 2013-01-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (4.301 Å) | Cite: | How insulin engages its primary binding site on the insulin receptor Nature, 493, 2013
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6VYV
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![BU of 6vyv by Molmil](/molmil-images/mine/6vyv) | |
6W09
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![BU of 6w09 by Molmil](/molmil-images/mine/6w09) | |
6W1C
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![BU of 6w1c by Molmil](/molmil-images/mine/6w1c) | |
5E1A
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![BU of 5e1a by Molmil](/molmil-images/mine/5e1a) | Structure of KcsA with L24C/R117C mutations | Descriptor: | POTASSIUM ION, antibody Fab fragment heavy chain, antibody Fab fragment light chain, ... | Authors: | Upadhyay, V, Kim, D.M, Nimigean, C.M. | Deposit date: | 2015-09-29 | Release date: | 2016-07-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Conformational heterogeneity in closed and open states of the KcsA potassium channel in lipid bicelles. J.Gen.Physiol., 148, 2016
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5DRW
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![BU of 5drw by Molmil](/molmil-images/mine/5drw) | |
5NJD
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![BU of 5njd by Molmil](/molmil-images/mine/5njd) | Structure of Interleukin 23 in complex with Briakinumab FAb | Descriptor: | Briakinumab FAb Heavy chain, Briakinumab FAb Light chain, Interleukin-12 subunit beta, ... | Authors: | Bloch, Y, Savvides, S.N. | Deposit date: | 2017-03-28 | Release date: | 2018-01-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12R beta 1. Immunity, 48, 2018
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5OGI
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![BU of 5ogi by Molmil](/molmil-images/mine/5ogi) | Complex of a binding protein and human adenovirus C 5 hexon | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | Authors: | Schmid, M, Ernst, P, Honegger, A, Suomalainen, M, Zimmermann, M, Braun, L, Stauffer, S, Thom, C, Dreier, B, Eibauer, M, Kipar, A, Vogel, V, Greber, U.F, Medalia, O, Plueckthun, A. | Deposit date: | 2017-07-13 | Release date: | 2018-02-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control. Nat Commun, 9, 2018
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3SGD
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![BU of 3sgd by Molmil](/molmil-images/mine/3sgd) | Crystal structure of the mouse mAb 17.2 | Descriptor: | CALCIUM ION, Heavy Chain, Light Chain | Authors: | Pizarro, J.C, Boulot, G, Hontebeyrie, M, Bentley, G.A. | Deposit date: | 2011-06-14 | Release date: | 2011-11-09 | Last modified: | 2013-01-23 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Crystal structure of the complex mAb 17.2 and the C-terminal region of Trypanosoma cruzi P2 Beta protein: implications in cross-reactivity Plos Negl Trop Dis, 5, 2011
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5I74
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![BU of 5i74 by Molmil](/molmil-images/mine/5i74) | X-ray structure of the ts3 human serotonin transporter complexed with Br-citalopram at the central site | Descriptor: | (1S)-1-(4-bromophenyl)-1-[3-(dimethylamino)propyl]-1,3-dihydro-2-benzofuran-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, ... | Authors: | Coleman, J.A, Green, E.M, Gouaux, E. | Deposit date: | 2016-02-16 | Release date: | 2016-04-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.395 Å) | Cite: | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
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5I6X
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![BU of 5i6x by Molmil](/molmil-images/mine/5i6x) | X-ray structure of the ts3 human serotonin transporter complexed with paroxetine at the central site | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ... | Authors: | Coleman, J.A, Green, E.M, Gouaux, E. | Deposit date: | 2016-02-16 | Release date: | 2016-04-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.14 Å) | Cite: | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
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5I75
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![BU of 5i75 by Molmil](/molmil-images/mine/5i75) | X-ray structure of the ts3 human serotonin transporter complexed with s-citalopram at the central site and Br-citalopram at the allosteric site | Descriptor: | (1S)-1-(4-bromophenyl)-1-[3-(dimethylamino)propyl]-1,3-dihydro-2-benzofuran-5-carbonitrile, (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Coleman, J.A, Green, E.M, Gouaux, E. | Deposit date: | 2016-02-16 | Release date: | 2016-04-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.49 Å) | Cite: | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
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5I71
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![BU of 5i71 by Molmil](/molmil-images/mine/5i71) | X-ray structure of the ts3 human serotonin transporter complexed with s-citalopram at the central site | Descriptor: | (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, ... | Authors: | Coleman, J.A, Green, E.M, Gouaux, E. | Deposit date: | 2016-02-16 | Release date: | 2016-04-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
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5I6Z
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![BU of 5i6z by Molmil](/molmil-images/mine/5i6z) | X-ray structure of the ts2 human serotonin transporter | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ... | Authors: | Coleman, J.A, Green, E.M, Gouaux, E. | Deposit date: | 2016-02-16 | Release date: | 2016-04-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (4.53 Å) | Cite: | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
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5I73
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![BU of 5i73 by Molmil](/molmil-images/mine/5i73) | X-ray structure of the ts3 human serotonin transporter complexed with s-citalopram at the central and allosteric sites | Descriptor: | (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-AMINOHEXANOIC ACID, ... | Authors: | Coleman, J.A, Green, E.M, Gouaux, E. | Deposit date: | 2016-02-16 | Release date: | 2016-04-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.24 Å) | Cite: | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
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7T6X
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![BU of 7t6x by Molmil](/molmil-images/mine/7t6x) | Cryo-EM structure of full-length hepatitis C virus E1E2 glycoprotein in complex with AR4A, AT12009, and IGH505 Fabs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AR4A Fab, ... | Authors: | Torrents de la Pena, A, Ward, A.B, Eshun-Wilson, L, Lander, G.C. | Deposit date: | 2021-12-14 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (3.83 Å) | Cite: | Structure of the hepatitis C virus E1E2 glycoprotein complex. Science, 378, 2022
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2Y7Q
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![BU of 2y7q by Molmil](/molmil-images/mine/2y7q) | THE HIGH-AFFINITY COMPLEX BETWEEN IGE AND ITS RECEPTOR FC EPSILON RI | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT ALPHA, IG EPSILON CHAIN C REGION, ... | Authors: | Davies, A.M, Holdom, M.D, Nettleship, J.E, Beavil, A.J, Owens, R.J, Sutton, B.J. | Deposit date: | 2011-02-01 | Release date: | 2011-04-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Conformational Changes in Ige Contribute to its Uniquely Slow Dissociation Rate from Receptor Fceri Nat.Struct.Mol.Biol., 18, 2011
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5LHR
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![BU of 5lhr by Molmil](/molmil-images/mine/5lhr) | The catalytic domain of murine urokinase-type plasminogen activator in complex with the active site binding inhibitory nanobody Nb22 | Descriptor: | Camelid-Derived Antibody Fragment Nb22, Urokinase-type plasminogen activator | Authors: | Kromann-Hansen, T, Lange, E.L, Sorensen, H.P, Ghassabeh, G.H, Huang, M, Jensen, J.K, Muyldermans, S, Declerck, P.J, Andreasen, P.A. | Deposit date: | 2016-07-12 | Release date: | 2017-06-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of a novel conformational equilibrium in urokinase-type plasminogen activator. Sci Rep, 7, 2017
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1HYS
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![BU of 1hys by Molmil](/molmil-images/mine/1hys) | CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH A POLYPURINE TRACT RNA:DNA | Descriptor: | 5'-D(*CP*TP*TP*TP*TP*CP*TP*TP*TP*TP*AP*AP*AP*AP*AP*GP*TP*GP*GP*CP*TP*G)-3', 5'-R(*UP*CP*AP*GP*CP*CP*AP*CP*UP*UP*UP*UP*UP*AP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3', FAB-28 MONOCLONAL ANTIBODY FRAGMENT HEAVY CHAIN, ... | Authors: | Sarafianos, S.G, Das, K, Tantillo, C, Clark Jr, A.D, Ding, J, Whitcomb, J, Boyer, P.L, Hughes, S.H, Arnold, E. | Deposit date: | 2001-01-22 | Release date: | 2001-03-26 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA. EMBO J., 20, 2001
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5M95
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![BU of 5m95 by Molmil](/molmil-images/mine/5m95) | STAPHYLOCOCCUS CAPITIS DIVALENT METAL ION TRANSPORTER (DMT) IN COMPLEX WITH MANGANESE | Descriptor: | CAMELID ANTIBODY FRAGMENT, NANOBODY, Divalent metal cation transporter MntH, ... | Authors: | Ehrnstorfer, I.A, Geertsma, E.R, Pardon, E, Steyaert, J, Dutzler, R. | Deposit date: | 2016-10-31 | Release date: | 2016-11-30 | Last modified: | 2019-09-25 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Crystal Structure Of A Slc11 (Nramp) Transporter Reveals The Basis For Transition-Metal Ion Transport. Nat.Struct.Mol.Biol., 21, 2014
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