5OGI

Complex of a binding protein and human adenovirus C 5 hexon

Summary for 5OGI

Entry DOI	10.2210/pdb5ogi/pdb
Descriptor	Hexon protein, scFv of 9C12 antibody, SULFATE ION, ... (7 entities in total)
Functional Keywords	antibody, human adenovirus c5, gene therapy, viral protein
Biological source	Mus musculus (House mouse) More
Cellular location	Virion : P04133
Total number of polymer chains	2
Total formula weight	137695.20
Authors	Schmid, M.,Ernst, P.,Honegger, A.,Suomalainen, M.,Zimmermann, M.,Braun, L.,Stauffer, S.,Thom, C.,Dreier, B.,Eibauer, M.,Kipar, A.,Vogel, V.,Greber, U.F.,Medalia, O.,Plueckthun, A. (deposition date: 2017-07-13, release date: 2018-02-07, Last modification date: 2024-01-17)
Primary citation	Schmid, M.,Ernst, P.,Honegger, A.,Suomalainen, M.,Zimmermann, M.,Braun, L.,Stauffer, S.,Thom, C.,Dreier, B.,Eibauer, M.,Kipar, A.,Vogel, V.,Greber, U.F.,Medalia, O.,Pluckthun, A. Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control. Nat Commun, 9:450-450, 2018 Cited by PubMed: 29386504 DOI: 10.1038/s41467-017-02707-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation