2Y7Q

THE HIGH-AFFINITY COMPLEX BETWEEN IGE AND ITS RECEPTOR FC EPSILON RI

Summary for 2Y7Q

• Entry DOI: 10.2210/pdb2y7q/pdb
• Related: 1F2Q 1F6A 1FP5 1G84 1IGE 1J86 1J87 1J88 1J89 1O0V 1RPQ
• Descriptor: HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT ALPHA, IG EPSILON CHAIN C REGION, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: allergy, antibody, ige-binding protein, high-affinity receptor, immunoglobulin c region, immune system
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 3
• Total formula weight: 95843.97

Authors

Davies, A.M.,Holdom, M.D.,Nettleship, J.E.,Beavil, A.J.,Owens, R.J.,Sutton, B.J. (deposition date: 2011-02-01, release date: 2011-04-20, Last modification date: 2023-12-20)

• Primary citation: Holdom, M.D.,Davies, A.M.,Nettleship, J.E.,Bagby, S.C.,Dhaliwal, B.,Girardi, E.,Hunt, J.,Gould, H.J.,Beavil, A.J.,Mcdonnell, J.M.,Owens, R.J.,Sutton, B.J.; Conformational Changes in Ige Contribute to its Uniquely Slow Dissociation Rate from Receptor Fceri; Nat.Struct.Mol.Biol., 18:571-, 2011; PubMed: 21516097; DOI: 10.1038/NSMB.2044

Experimental method

X-RAY DIFFRACTION (3.4 Å)