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6E0C	Cryo-EM structure of the CENP-A nucleosome (W601) in complex with a single chain antibody fragment Descriptor: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Yadav, K.N.S, Zhou, B.-R. Deposit date: 2018-07-06 Release date: 2019-05-22 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (2.63 Å) Cite: Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment. Nat Commun, 10, 2019
1PO6	Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI) Descriptor: 5'-D(*T*AP*GP*GP*(6MI)P*TP*TP*AP*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1 Authors: Myers, J.C, Moore, S.A, Shamoo, Y. Deposit date: 2003-06-13 Release date: 2003-11-11 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures J.BIOL.CHEM., 278, 2003
1PKM	THE REFINED THREE-DIMENSIONAL STRUCTURE OF CAT MUSCLE (M1) PYRUVATE KINASE, AT A RESOLUTION OF 2.6 ANGSTROMS Descriptor: M1 PYRUVATE KINASE Authors: Allen, S.C, Muirhead, H. Deposit date: 1995-07-13 Release date: 1995-10-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Refined three-dimensional structure of cat-muscle (M1) pyruvate kinase at a resolution of 2.6 A. Acta Crystallogr.,Sect.D, 52, 1996
1PKN	STRUCTURE OF RABBIT MUSCLE PYRUVATE KINASE COMPLEXED WITH MN2+, K+, AND PYRUVATE Descriptor: MANGANESE (II) ION, POTASSIUM ION, PYRUVATE KINASE, ... Authors: Larsen, T.M, Laughlin, L.T, Holden, H.M, Rayment, I, Reed, G.H. Deposit date: 1994-03-25 Release date: 1995-01-26 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure of rabbit muscle pyruvate kinase complexed with Mn2+, K+, and pyruvate. Biochemistry, 33, 1994
7W5B	The cryo-EM structure of human C* complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2021-11-29 Release date: 2022-06-22 Last modified: 2022-08-17 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
7W5A	The cryo-EM structure of human pre-C*-II complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2021-11-29 Release date: 2022-06-22 Last modified: 2022-08-17 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
7WU7	Prefoldin-tubulin-TRiC complex Descriptor: ADENOSINE-5'-DIPHOSPHATE, Prefoldin subunit 1, Prefoldin subunit 2, ... Authors: Gestaut, D, Zhao, Y, Park, J, Ma, B, Leitner, A, Collier, M, Pintilie, G, Roh, S.-H, Chiu, W, Frydman, J. Deposit date: 2022-02-07 Release date: 2022-12-21 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (3.85 Å) Cite: Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
7WZ3	Cryo-EM structure of human TRiC-tubulin-S1 state Descriptor: ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... Authors: Cong, Y, Liu, C.X. Deposit date: 2022-02-16 Release date: 2023-02-22 Last modified: 2023-07-05 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM. Commun Biol, 6, 2023
7X3U	cryo-EM structure of human TRiC-ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... Authors: Cong, Y, Liu, C.X. Deposit date: 2022-03-01 Release date: 2023-06-07 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM. Commun Biol, 6, 2023
7X3J	Cryo-EM structure of human TRiC-tubulin-S2 Descriptor: ADENOSINE-5'-TRIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... Authors: Cong, Y, Liu, C.X. Deposit date: 2022-03-01 Release date: 2023-06-07 Last modified: 2023-07-05 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM. Commun Biol, 6, 2023
7X6Q	cryo-EM structure of human TRiC-ATP-closed state Descriptor: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... Authors: Cong, Y, Liu, C.X. Deposit date: 2022-03-08 Release date: 2023-06-07 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM. Commun Biol, 6, 2023
7X7Y	Cryo-EM structure of Human TRiC-ATP-open state Descriptor: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... Authors: Cong, Y, Liu, C.X. Deposit date: 2022-03-10 Release date: 2023-06-07 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM. Commun Biol, 6, 2023
7WTW	Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A3 Descriptor: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. Deposit date: 2022-02-05 Release date: 2022-10-19 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
7WTT	Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (with CK1) Descriptor: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. Deposit date: 2022-02-05 Release date: 2022-10-19 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
7WTU	Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (without CK1) Descriptor: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. Deposit date: 2022-02-05 Release date: 2022-10-19 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (3 Å) Cite: The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
7XNY	High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... Authors: Cheng, J, Beckmann, R. Deposit date: 2022-04-30 Release date: 2023-04-05 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia. Cancer Discov, 13, 2023
7X0A	Cryo-EM structure of human TRiC-NPP state Descriptor: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... Authors: Cong, Y, Liu, C.X. Deposit date: 2022-02-21 Release date: 2023-04-12 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM. Commun Biol, 6, 2023
7XNX	High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... Authors: Cheng, J, Beckmann, R. Deposit date: 2022-04-30 Release date: 2023-04-05 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia. Cancer Discov, 13, 2023
7YCX	The structure of INTAC-PEC complex Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase II subunit RPB1, ... Authors: Zheng, H, Jin, Q, Wang, X, Qi, Y, Liu, W, Ren, Y, Zhao, D, Chen, F.X, Cheng, J, Chen, X, Xu, Y. Deposit date: 2022-07-02 Release date: 2023-03-15 Last modified: 2023-09-27 Method: ELECTRON MICROSCOPY (4.18 Å) Cite: Structural basis of INTAC-regulated transcription. Protein Cell, 14, 2023
7Y5V	Cryo-EM structure of the dimeric human CAF1LC-H3-H4 complex Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... Authors: Liu, C.P, Yu, C, Yu, Z.Y, Xu, R.M. Deposit date: 2022-06-17 Release date: 2023-08-16 Last modified: 2023-09-06 Method: ELECTRON MICROSCOPY (6.1 Å) Cite: Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
7Y5U	Cryo-EM structure of the monomeric human CAF1LC-H3-H4 complex Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... Authors: Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M. Deposit date: 2022-06-17 Release date: 2023-08-16 Last modified: 2023-09-06 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
5F6D	Crystal structure of Ubc9 (K48A/K49A/E54A) complexed with Fragment 6 Descriptor: 6~{H}-benzo[c][1,2]benzothiazine 5,5-dioxide, SUMO-conjugating enzyme UBC9 Authors: Lountos, G.T, Hewitt, W.M, Zlotkowski, K, Dahlhauser, S, Saunders, L.B, Needle, D, Tropea, J.E, Zhan, C, Wei, G, Ma, B, Nussinov, R, Schneekloth, J.S.Jr, Waugh, D.S. Deposit date: 2015-12-05 Release date: 2016-04-27 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.553 Å) Cite: Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9. Angew.Chem.Int.Ed.Engl., 55, 2016
5F6W	Crystal structure of Ubc9 (K48/K49A/E54A) complexed with Fragment 1 (biphenol) Descriptor: 2-(2-hydroxyphenyl)phenol, SUMO-conjugating enzyme UBC9 Authors: Lountos, G.T, Hewitt, W.M, Zlotkowski, K, Dahlhauser, S, Saunders, L.B, Needle, D, Tropea, J.E, Zhan, C, Wei, G, Ma, B, Nussinov, R, Schneekloth, J.S.Jr, Waugh, D.S. Deposit date: 2015-12-07 Release date: 2016-04-27 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.699 Å) Cite: Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9. Angew.Chem.Int.Ed.Engl., 55, 2016
7YYH	Structure of the human CCANdeltaT CENP-A alpha-satellite complex Descriptor: Centromere protein C, Centromere protein H, Centromere protein I, ... Authors: Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. Deposit date: 2022-02-17 Release date: 2022-05-18 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (8.9 Å) Cite: Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
5F6V	Crystal structure of Ubc9 (K48/K49A/E54A) complexed with Fragment 1 (biphenol from fragment cocktail screen) Descriptor: 2-(2-hydroxyphenyl)phenol, SUMO-conjugating enzyme UBC9 Authors: Lountos, G.T, Hewitt, W.M, Zlotkowski, K, Dahlhauser, S, Saunders, L.B, Needle, D, Tropea, J.E, Zhan, C, Wei, G, Ma, B, Nussinov, R, Schneekloth, J.S.Jr, Waugh, D.S. Deposit date: 2015-12-07 Release date: 2016-04-27 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.492 Å) Cite: Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9. Angew.Chem.Int.Ed.Engl., 55, 2016

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