7XNY

High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells

This is a non-PDB format compatible entry.

Summary for 7XNY

• Entry DOI: 10.2210/pdb7xny/pdb
• EMDB information: 33330
• Descriptor: 28S rRNA, 60S ribosomal protein L7a, 60S ribosomal protein L9, ... (83 entities in total)
• Functional Keywords: ribosome, rrna ribomethylome
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 79
• Total formula weight: 3792720.06

Authors

Cheng, J.,Beckmann, R. (deposition date: 2022-04-30, release date: 2023-04-05)

• Primary citation: Zhou, F.,Aroua, N.,Liu, Y.,Rohde, C.,Cheng, J.,Wirth, A.K.,Fijalkowska, D.,Gollner, S.,Lotze, M.,Yun, H.,Yu, X.,Pabst, C.,Sauer, T.,Oellerich, T.,Serve, H.,Rollig, C.,Bornhauser, M.,Thiede, C.,Baldus, C.,Frye, M.,Raffel, S.,Krijgsveld, J.,Jeremias, I.,Beckmann, R.,Trumpp, A.,Muller-Tidow, C.; A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia.; Cancer Discov, 13:332-347, 2023; PubMed: 36259929; DOI: 10.1158/2159-8290.CD-22-0210

Experimental method

ELECTRON MICROSCOPY (2.5 Å)