PDB: 3074 resultsInfo pagesStatus searchChemie searchBIRD

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2LSR	Solution structure of harmonin N terminal domain in complex with a exon68 encoded peptide of cadherin23 Descriptor: Harmonin, peptide from Cadherin-23 Authors: Pan, L, Wu, L, Zhang, C, Zhang, M. Deposit date: 2012-05-04 Release date: 2012-08-15 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Large protein assemblies formed by multivalent interactions between cadherin23 and harmonin suggest a stable anchorage structure at the tip link of stereocilia. J.Biol.Chem., 287, 2012
2L7T	Solution structure of the MFS-bound Sans CEN2 peptide Descriptor: MFS-bound Sans CEN2 peptide Authors: Pan, L, Wu, L, Wei, Z, Zhang, M. Deposit date: 2010-12-22 Release date: 2011-03-02 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo. Science, 331, 2011
2MXP	Solution structure of NDP52 ubiquitin-binding zinc finger Descriptor: Calcium-binding and coiled-coil domain-containing protein 2, ZINC ION Authors: Pan, L, Xie, X. Deposit date: 2015-01-12 Release date: 2015-11-11 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Molecular basis of ubiquitin recognition by the autophagy receptor CALCOCO2 Autophagy, 11, 2015
3CYY	The crystal structure of ZO-1 PDZ2 in complex with the Cx43 peptide Descriptor: Tight junction protein ZO-1, peptide from Gap junction alpha-1 protein Authors: Pan, L, Zhang, M. Deposit date: 2008-04-27 Release date: 2008-09-23 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites Embo J., 27, 2008
5UBY	Fab structure of anti-HIV-1 gp120 mAb 1A8 Descriptor: Heavy chain of Fab fragment of anti-HIV1 gp120 mAb 1A8, Light chain of Fab fragment of anti-HIV1 gp120 mAb 1A8 Authors: Pan, R, Kong, X.-P. Deposit date: 2016-12-21 Release date: 2018-01-10 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.6 Å) Cite: High Antibody Diversity and Low Inter-clonal Competition Favor Production of Functional Neutralizing Antibodies To be Published
5UBZ	Fab structure of HIV gp120 specific mAb 1E12 Descriptor: Anti-HIV1 gp120 mAb 1E12 Fab heavy chain, Anti-HIV1 gp120 mAb 1E12 Fab light chain Authors: Pan, R, Kong, X.-P. Deposit date: 2016-12-21 Release date: 2018-01-10 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.75 Å) Cite: High Antibody Diversity and Low Inter-clonal Competition Favor Production of Functional Neutralizing Antibodies To be published
3TOE	Structure of Mth10b Descriptor: DNA/RNA-binding protein Alba Authors: Pan, X.M, Zhang, N, Liu, Y.F, Liu, X. Deposit date: 2011-09-05 Release date: 2012-04-25 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.197 Å) Cite: Molecular mechanism underlying the interaction of typical Sac10b family proteins with DNA. Plos One, 7, 2012
6VU2	M1214_N1 Fab structure Descriptor: M1214 N1 Fab heavy chain, M1214 N1 Fab light chain Authors: Pan, R, Kong, X. Deposit date: 2020-02-14 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.19 Å) Cite: VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA. Cell Host Microbe, 27, 2020
4D9L	Fab structure of anti-HIV-1 gp120 V2 mAb 697 Descriptor: Heavy chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697, Light chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697 Authors: Pan, R.M, Kong, X.P. Deposit date: 2012-01-11 Release date: 2012-03-21 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.485 Å) Cite: Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals. Virology, 427, 2012
4F58	Fab structure of a neutralizing antibody L3 from an early subtype A HIV-1 infected patient Descriptor: Heavy chain of Fab of a neutralizing antibody L3, Light chain of Fab of a neutralizing antibody L3, SULFATE ION Authors: Pan, R.M, Kong, X.P. Deposit date: 2012-05-12 Release date: 2013-03-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.488 Å) Cite: Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth. Plos Pathog., 9, 2013
4F57	Fab structure of a neutralizing antibody L1 from an early subtype A HIV-1 infected patient Descriptor: GLYCEROL, Heavy chain of Fab of a neutralizing antibody L1, Light chain of Fab of a neutralizing antibody L1 Authors: Pan, R.M, Kong, X.P. Deposit date: 2012-05-12 Release date: 2013-03-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth. Plos Pathog., 9, 2013
5BTU	The structure of Diels-Alderase PyrI4 in the biosynthetic pathway of pyrroindomycins Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, PyrI4 Authors: Pan, L, Guo, Y, Liu, J. Deposit date: 2015-06-03 Release date: 2016-02-24 Last modified: 2016-03-30 Method: X-RAY DIFFRACTION (2.503 Å) Cite: Enzyme-Dependent [4 + 2] Cycloaddition Depends on Lid-like Interaction of the N-Terminal Sequence with the Catalytic Core in PyrI4 Cell Chem Biol, 23, 2016
5BU3	Crystal Structure of Diels-Alderase PyrI4 in complex with its product Descriptor: (4S,4aS,6aS,8R,9R,10aR,13R,14aS,18aR,18bR)-9-ethyl-4,8,19-trihydroxy-10a,12,13,18a-tetramethyl-2,3,4,4a,5,6,6a,7,8,9,10,10a,13,14,18a,18b-hexadecahydro-1H-14a,17-(metheno)benzo[b]naphtho[2,1-h]azacyclododecine-16,18(15H,17H)-dione, GLYCEROL, PyrI4 Authors: Pan, L, Guo, Y, Liu, J. Deposit date: 2015-06-03 Release date: 2016-02-24 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.897 Å) Cite: Enzyme-Dependent [4 + 2] Cycloaddition Depends on Lid-like Interaction of the N-Terminal Sequence with the Catalytic Core in PyrI4 Cell Chem Biol, 23, 2016
5XGV	The structure of Diels-Alderase PyrE3 in the biosynthetic pathway of pyrroindomycins Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, PyrE3 Authors: Pan, L, Gong, Y, Guo, Y. Deposit date: 2017-04-18 Release date: 2018-04-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.099 Å) Cite: Structural Insights into a Flavin-Dependent [4 + 2] Cyclase that Catalyzes trans-Decalin Formation in Pyrroindomycin Biosynthesis. Cell Chem Biol, 25, 2018
5YT6	Crystal structure of TAX1BP1 UBZ2 in complex with mono-ubiquitin Descriptor: 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... Authors: Pan, L, Hu, S. Deposit date: 2017-11-17 Release date: 2018-07-11 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.501 Å) Cite: Mechanistic Insights into Recognitions of Ubiquitin and Myosin VI by Autophagy Receptor TAX1BP1. J. Mol. Biol., 430, 2018
5ZFL	Crystal structure of beta-lactamase PenP mutant E166Y Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase Authors: Pan, X, Zhao, Y. Deposit date: 2018-03-06 Release date: 2019-03-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The hydrolytic water molecule of Class A beta-lactamase relies on the acyl-enzyme intermediate ES* for proper coordination and catalysis. Sci Rep, 10, 2020
5ZG6	Crystal structure of beta-lactamase PenP mutant-E166Y in complex with cephaloridine as "post-acylation" intermediate Descriptor: 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase Authors: Pan, X, Zhao, Y. Deposit date: 2018-03-07 Release date: 2019-03-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2 Å) Cite: The hydrolytic water molecule of Class A beta-lactamase relies on the acyl-enzyme intermediate ES* for proper coordination and catalysis. Sci Rep, 10, 2020
5ZFT	Crystal structure of beta-lactamase PenP mutant-E166Y in complex with cephaloridine as "pre-deacylation" intermediate Descriptor: 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase Authors: Pan, X, Zhao, Y. Deposit date: 2018-03-07 Release date: 2019-03-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.93 Å) Cite: The hydrolytic water molecule of Class A beta-lactamase relies on the acyl-enzyme intermediate ES* for proper coordination and catalysis. Sci Rep, 10, 2020
3IVH	Design and Synthesis of Potent BACE-1 Inhibitors with Cellular Activity: Structure-Activity Relationship of P1 Substituents Descriptor: Beta-secretase 1, N-[(1S,2R)-3-{[1-(3-tert-butylphenyl)cyclohexyl]amino}-1-(3,5-difluorobenzyl)-2-hydroxypropyl]acetamide Authors: Pan, H. Deposit date: 2009-09-01 Release date: 2010-01-05 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Design and synthesis of cell potent BACE-1 inhibitors: structure-activity relationship of P1' substituents. Bioorg.Med.Chem.Lett., 19, 2009
3IVI	Design and Synthesis of Potent BACE-1 Inhibitors with Cellular Activity: Structure-Activity Relationship of P1 Substituents Descriptor: Beta-secretase 1, GLYCEROL, N-[(1S,2R)-3-{[(5S)-5-(3-tert-butylphenyl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]amino}-1-(3,5-difluorobenzyl)-2-hydroxypropyl]acetamide, ... Authors: Pan, H. Deposit date: 2009-09-01 Release date: 2010-01-05 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Design and synthesis of cell potent BACE-1 inhibitors: structure-activity relationship of P1' substituents. Bioorg.Med.Chem.Lett., 19, 2009
3K1R	Structure of harmonin NPDZ1 in complex with the SAM-PBM of Sans Descriptor: Harmonin, Usher syndrome type-1G protein Authors: Pan, L, Yan, J, Zhang, M. Deposit date: 2009-09-28 Release date: 2010-01-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins Proc.Natl.Acad.Sci.USA, 107, 2010
7KFV	Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B12 Fab) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody C1A-B12 Fab, Spike glycoprotein, ... Authors: Pan, J, Abraham, J, Clark, L, Clark, S. Deposit date: 2020-10-15 Release date: 2020-12-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.102 Å) Cite: Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2. Biorxiv, 2020
7KFY	Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-F10 Fab) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, heavy chain of human antibody C1A-F10 Fab, ... Authors: Pan, J, Abraham, J, Clark, L, Clark, S. Deposit date: 2020-10-15 Release date: 2020-12-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.157 Å) Cite: Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2. Biorxiv, 2020
7KFW	Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B3 Fab) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, heavy chain of antibody C1A-B3 Fab, ... Authors: Pan, J, Abraham, J, Clark, L, Clark, S. Deposit date: 2020-10-15 Release date: 2020-12-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.792 Å) Cite: Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2. Biorxiv, 2020
7KFX	Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-C2 Fab) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, heavy chain of human antibody C1A-C2 Fab, ... Authors: Pan, J, Abraham, J, Clark, L, Clark, S. Deposit date: 2020-10-15 Release date: 2020-12-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.226 Å) Cite: Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2. Biorxiv, 2020

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