5ZFL
Crystal structure of beta-lactamase PenP mutant E166Y
Summary for 5ZFL
Entry DOI | 10.2210/pdb5zfl/pdb |
Descriptor | Beta-lactamase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | class a beta-lactamase, antibiotic resistance, hydrolase |
Biological source | Bacillus licheniformis |
Total number of polymer chains | 2 |
Total formula weight | 60801.07 |
Authors | |
Primary citation | He, Y.,Lei, J.,Pan, X.,Huang, X.,Zhao, Y. The hydrolytic water molecule of Class A beta-lactamase relies on the acyl-enzyme intermediate ES* for proper coordination and catalysis. Sci Rep, 10:10205-10205, 2020 Cited by PubMed: 32576842DOI: 10.1038/s41598-020-66431-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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