5UBZ

Fab structure of HIV gp120 specific mAb 1E12

Summary for 5UBZ

• Entry DOI: 10.2210/pdb5ubz/pdb
• Related: 5UBY
• Descriptor: Anti-HIV1 gp120 mAb 1E12 Fab heavy chain, Anti-HIV1 gp120 mAb 1E12 Fab light chain (3 entities in total)
• Functional Keywords: hiv, gp120, antibody, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 46750.01

Authors

Pan, R.,Kong, X.-P. (deposition date: 2016-12-21, release date: 2018-01-10, Last modification date: 2023-10-04)

• Primary citation: Smith, S.A.,Burton, S.L.,Spicer, L.,Pan, R.,Kilembe, W.,Lakhi, S.,Karita, E.,Price, M.,Allen, S.,Hunter, E.,Kong, X.-P.,Derdeyn, C.A.; High Antibody Diversity and Low Inter-clonal Competition Favor Production of Functional Neutralizing Antibodies; To be published,

Experimental method

X-RAY DIFFRACTION (2.75 Å)