5BTU

The structure of Diels-Alderase PyrI4 in the biosynthetic pathway of pyrroindomycins

Summary for 5BTU

• Entry DOI: 10.2210/pdb5btu/pdb
• Related: 5BU3
• Descriptor: PyrI4, GLYCEROL, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
• Functional Keywords: beta-barrel, diels-alderase, pyrroindomycins, lyase
• Biological source: Streptomyces rugosporus
• Total number of polymer chains: 2
• Total formula weight: 40383.60

Authors

Pan, L.,Guo, Y.,Liu, J. (deposition date: 2015-06-03, release date: 2016-02-24, Last modification date: 2016-03-30)

• Primary citation: Zheng, Q.,Guo, Y.,Yang, L.,Zhao, Z.,Wu, Z.,Zhang, H.,Liu, J.,Cheng, X.,Wu, J.,Yang, H.,Jiang, H.,Pan, L.,Liu, W.; Enzyme-Dependent [4 + 2] Cycloaddition Depends on Lid-like Interaction of the N-Terminal Sequence with the Catalytic Core in PyrI4; Cell Chem Biol, 23:352-360, 2016; PubMed: 26877021; DOI: 10.1016/j.chembiol.2016.01.005

Experimental method

X-RAY DIFFRACTION (2.503 Å)