6B70
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![BU of 6b70 by Molmil](/molmil-images/mine/6b70) | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain and insulin | 分子名称: | FAB H11-E heavy chain, FAB H11-E light chain, Insulin, ... | 著者 | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | 登録日 | 2017-10-03 | 公開日 | 2017-12-27 | 最終更新日 | 2021-04-28 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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6BF8
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![BU of 6bf8 by Molmil](/molmil-images/mine/6bf8) | Cryo-EM structure of human insulin degrading enzyme in complex with insulin | 分子名称: | Insulin-degrading enzyme | 著者 | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | 登録日 | 2017-10-26 | 公開日 | 2018-04-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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6BFC
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![BU of 6bfc by Molmil](/molmil-images/mine/6bfc) | Cryo-EM structure of human insulin degrading enzyme in complex with insulin | 分子名称: | Insulin, Insulin-degrading enzyme | 著者 | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | 登録日 | 2017-10-26 | 公開日 | 2017-12-27 | 最終更新日 | 2021-04-28 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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6B3Q
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![BU of 6b3q by Molmil](/molmil-images/mine/6b3q) | Cryo-EM structure of human insulin degrading enzyme in complex with insulin | 分子名称: | Insulin, Insulin-degrading enzyme | 著者 | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | 登録日 | 2017-09-22 | 公開日 | 2017-11-22 | 最終更新日 | 2021-04-28 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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6B7Y
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![BU of 6b7y by Molmil](/molmil-images/mine/6b7y) | Cryo-EM structure of human insulin degrading enzyme | 分子名称: | Insulin-degrading enzyme | 著者 | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | 登録日 | 2017-10-05 | 公開日 | 2017-11-08 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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6BF6
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![BU of 6bf6 by Molmil](/molmil-images/mine/6bf6) | Cryo-EM structure of human insulin degrading enzyme | 分子名称: | Insulin-degrading enzyme | 著者 | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | 登録日 | 2017-10-26 | 公開日 | 2018-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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6B7Z
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![BU of 6b7z by Molmil](/molmil-images/mine/6b7z) | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11 heavy chain and FAB H11 light chain | 分子名称: | FAB H11 heavy chain, FAB H11 light chain, Insulin-degrading enzyme | 著者 | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | 登録日 | 2017-10-05 | 公開日 | 2018-01-10 | 最終更新日 | 2021-04-28 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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6BF9
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![BU of 6bf9 by Molmil](/molmil-images/mine/6bf9) | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain | 分子名称: | Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme | 著者 | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | 登録日 | 2017-10-26 | 公開日 | 2018-02-07 | 最終更新日 | 2021-04-28 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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6BF7
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![BU of 6bf7 by Molmil](/molmil-images/mine/6bf7) | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain | 分子名称: | Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme | 著者 | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | 登録日 | 2017-10-26 | 公開日 | 2018-02-07 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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6C6D
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![BU of 6c6d by Molmil](/molmil-images/mine/6c6d) | |
7RZH
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![BU of 7rzh by Molmil](/molmil-images/mine/7rzh) | Insulin Degrading Enzyme O/O | 分子名称: | Cysteine-free Insulin-degrading enzyme | 著者 | Mancl, J.M, Liang, W.G, Tang, W.J. | 登録日 | 2021-08-27 | 公開日 | 2022-08-31 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme To be published
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7RZI
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![BU of 7rzi by Molmil](/molmil-images/mine/7rzi) | Insulin Degrading Enzyme pC/pC | 分子名称: | Cysteine-free Insulin-degrading enzyme, Insulin A chain, Insulin B chain | 著者 | Mancl, J.M, Liang, W.G, Tang, W.J. | 登録日 | 2021-08-27 | 公開日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme To be published
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7RZE
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![BU of 7rze by Molmil](/molmil-images/mine/7rze) | Insulin Degrading Enzyme pO/pC | 分子名称: | Cysteine-free Insulin-degrading enzyme, Insulin A chain, Insulin B chain | 著者 | Mancl, J.M, Liang, W.G, Tang, W.J. | 登録日 | 2021-08-27 | 公開日 | 2022-08-31 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme To be published
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7RZF
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![BU of 7rzf by Molmil](/molmil-images/mine/7rzf) | Insulin Degrading Enzyme O/pC | 分子名称: | Cysteine-free Insulin-degrading enzyme, Insulin A chain, Insulin B chain | 著者 | Mancl, J.M, Liang, W.G, Tang, W.J. | 登録日 | 2021-08-27 | 公開日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme To be published
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7RZG
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![BU of 7rzg by Molmil](/molmil-images/mine/7rzg) | Insulin Degrading Enzyme O/pO | 分子名称: | Cysteine-free Insulin-degrading enzyme | 著者 | Mancl, J.M, Liang, W.G, Tang, W.J. | 登録日 | 2021-08-27 | 公開日 | 2022-08-31 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme To be published
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7K1V
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![BU of 7k1v by Molmil](/molmil-images/mine/7k1v) | |
5WOB
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![BU of 5wob by Molmil](/molmil-images/mine/5wob) | Crystal Structure Analysis of Fab1-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Insulin | 分子名称: | IDE-bound Fab heavy chain, IDE-bound Fab light chain, Insulin, ... | 著者 | McCord, L.A, Liang, W.G, Farcasanu, M, Wang, A.G, Koide, S, Tang, W.J. | 登録日 | 2017-08-01 | 公開日 | 2018-04-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.95 Å) | 主引用文献 | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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4RPU
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![BU of 4rpu by Molmil](/molmil-images/mine/4rpu) | Crystal Structure of Human Presequence Protease in Complex with Inhibitor MitoBloCK-60 | 分子名称: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | 著者 | Mo, S.M, Liang, W.G, King, J.V, Wijaya, J, Koehler, C.M, Tang, W.J. | 登録日 | 2014-10-31 | 公開日 | 2015-12-09 | 実験手法 | X-RAY DIFFRACTION (2.265 Å) | 主引用文献 | Crystal Structure of Human Presequence Protease in Complex with Inhibitor MitoBloCK-60 TO BE PUBLISHED
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4IOF
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![BU of 4iof by Molmil](/molmil-images/mine/4iof) | Crystal structure analysis of Fab-bound human Insulin Degrading Enzyme (IDE) | 分子名称: | Fab-bound IDE, heavy chain, light chain, ... | 著者 | McCord, L.A, Liang, W.G, Hoey, R, Dowdell, E, Koide, A, Koide, S, Tang, W.J. | 登録日 | 2013-01-07 | 公開日 | 2013-07-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.353 Å) | 主引用文献 | Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme. Proc.Natl.Acad.Sci.USA, 110, 2013
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4L3T
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![BU of 4l3t by Molmil](/molmil-images/mine/4l3t) | Crystal Structure of Substrate-free Human Presequence Protease | 分子名称: | ACETATE ION, GLYCEROL, Presequence protease, ... | 著者 | King, J.V, Liang, W.G, Tang, W.J. | 登録日 | 2013-06-06 | 公開日 | 2013-07-03 | 最終更新日 | 2014-07-23 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Molecular basis of substrate recognition and degradation by human presequence protease. Structure, 22, 2014
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4NGE
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![BU of 4nge by Molmil](/molmil-images/mine/4nge) | Crystal Structure of Human Presequence Protease in Complex with Amyloid-beta (1-40) | 分子名称: | ACETATE ION, Beta-amyloid protein 40, GLYCEROL, ... | 著者 | King, J.V, Liang, W.G, Tang, W.J. | 登録日 | 2013-11-01 | 公開日 | 2014-05-14 | 最終更新日 | 2014-07-23 | 実験手法 | X-RAY DIFFRACTION (2.704 Å) | 主引用文献 | Molecular basis of substrate recognition and degradation by human presequence protease. Structure, 22, 2014
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