7RZH

Insulin Degrading Enzyme O/O

Summary for 7RZH

• Entry DOI: 10.2210/pdb7rzh/pdb
• EMDB information: 24760
• Descriptor: Cysteine-free Insulin-degrading enzyme (1 entity in total)
• Functional Keywords: m16a zinc metalloprotease, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 234137.02

Authors

Mancl, J.M.,Liang, W.G.,Tang, W.J. (deposition date: 2021-08-27, release date: 2022-08-31, Last modification date: 2025-06-04)

• Primary citation: Mancl, J.M.,Liang, W.G.,Wei, H.,Carragher, B.,Potter, C.S.,Tang, W.J.; Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme; To be published,

Experimental method

ELECTRON MICROSCOPY (3.8 Å)