7RZH
Insulin Degrading Enzyme O/O
Summary for 7RZH
Entry DOI | 10.2210/pdb7rzh/pdb |
EMDB information | 24760 |
Descriptor | Cysteine-free Insulin-degrading enzyme (1 entity in total) |
Functional Keywords | m16a zinc metalloprotease, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 234137.02 |
Authors | Mancl, J.M.,Liang, W.G.,Tang, W.J. (deposition date: 2021-08-27, release date: 2022-08-31, Last modification date: 2024-06-05) |
Primary citation | Mancl, J.M.,Liang, W.G.,Wei, H.,Carragher, B.,Potter, C.S.,Tang, W.J. Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme To be published, |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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