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7RZF

Insulin Degrading Enzyme O/pC

Summary for 7RZF
Entry DOI10.2210/pdb7rzf/pdb
Related7RZF 7RZG 7RZH 7RZI
EMDB information24758
DescriptorCysteine-free Insulin-degrading enzyme, Insulin A chain, Insulin B chain (3 entities in total)
Functional Keywordsm16a zinc metalloprotease, hydrolase
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight239938.65
Authors
Mancl, J.M.,Liang, W.G.,Tang, W.J. (deposition date: 2021-08-27, release date: 2022-08-31)
Primary citationMancl, J.M.,Liang, W.G.,Wei, H.,Carragher, B.,Potter, C.S.,Tang, W.J.
Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme
To be published,
Experimental method
ELECTRON MICROSCOPY (3.4 Å)
Structure validation

217705

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