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PDB: 293 results

8HKN
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Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to approved drug Fluzoparib
Descriptor: Fluzoparib, GLYCEROL, Poly [ADP-ribose] polymerase 2
Authors:Wang, X.Y, Zhou, J, Xu, B.L.
Deposit date:2022-11-27
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to approved drug Fluzoparib
To Be Published
8HLQ
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Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Niraparib (MK-4827)
Descriptor: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide, GLYCEROL, Poly [ADP-ribose] polymerase 2
Authors:Wang, X.Y, Zhou, J, Xu, B.L.
Deposit date:2022-11-30
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Niraparib (MK-4827)
To Be Published
8HLJ
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BU of 8hlj by Molmil
Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Olaparib (AZD2281)
Descriptor: 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one, Poly [ADP-ribose] polymerase 2
Authors:Wang, X.Y, Zhou, J, Xu, B.L.
Deposit date:2022-11-30
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Olaparib (AZD2281)
To Be Published
8HKO
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BU of 8hko by Molmil
Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Rucaparib
Descriptor: GLYCEROL, Poly [ADP-ribose] polymerase 2, Rucaparib
Authors:Wang, X.Y, Zhou, J, Xu, B.L.
Deposit date:2022-11-27
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Rucaparib
To Be Published
8HKS
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BU of 8hks by Molmil
Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Pamiparib(BGB-290)
Descriptor: (2R)-14-fluoro-2-methyl-6,9,10,19-tetrazapentacyclo[14.2.1.02,6.08,18.012,17]nonadeca-1(18),8,12(17),13,15-pentaen-11-one, GLYCEROL, Poly [ADP-ribose] polymerase 2
Authors:Wang, X.Y, Zhou, J, Xu, B.L.
Deposit date:2022-11-28
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Pamiparib
To Be Published
8HLR
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Human ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to Fluzoparib (SHR3162)
Descriptor: Fluzoparib, Poly [ADP-ribose] polymerase 1, processed C-terminus, ...
Authors:Wang, X.Y, Zhou, J, Xu, B.L.
Deposit date:2022-11-30
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Human ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to Fluzoparib (SHR3162)
To Be Published
2IS9
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BU of 2is9 by Molmil
Structure of yeast DCN-1
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Defective in cullin neddylation protein 1, ...
Authors:Yang, X, Zhou, J, Sun, L, Wei, Z, Gao, J, Gong, W, Xu, R.M, Rao, Z, Liu, Y.
Deposit date:2006-10-16
Release date:2007-06-26
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis for the function of DCN-1 in protein Neddylation.
J.Biol.Chem., 282, 2007
3WFV
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BU of 3wfv by Molmil
HIV-1 CRF07 gp41
Descriptor: Envelope glycoprotein gp160
Authors:Du, J, Xue, H, Ma, J, Liu, F, Zhou, J, Shao, Y, Qiao, W, Liu, X.
Deposit date:2013-07-24
Release date:2013-10-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of HIV CRF07 B'/C gp41 reveals a hyper-mutant site in the middle of HR2 heptad repeat
Virology, 446, 2013
3V0A
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BU of 3v0a by Molmil
2.7 angstrom crystal structure of BoNT/Ai in complex with NTNHA
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BoNT/A, CALCIUM ION, ...
Authors:Gu, S, Rumpel, S, Zhou, J, Strotmeier, J, Bigalke, H, Perry, K, Shoemaker, C.B, Rummel, A, Jin, R.
Deposit date:2011-12-07
Release date:2012-03-14
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.
Science, 335, 2012
2HZ6
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BU of 2hz6 by Molmil
The crystal structure of human IRE1-alpha luminal domain
Descriptor: Endoplasmic reticulum to nucleus signalling 1 isoform 1 variant
Authors:Kaufman, R.J, Xu, Z, Zhou, J.
Deposit date:2006-08-08
Release date:2006-08-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3V0B
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BU of 3v0b by Molmil
3.9 angstrom crystal structure of BoNT/Ai in complex with NTNHA
Descriptor: BoNT/A, CALCIUM ION, NTNH, ...
Authors:Gu, S, Rumpel, S, Zhou, J, Strotmeier, J, Bigalke, H, Perry, K, Shoemaker, C.B, Rummel, A, Jin, R.
Deposit date:2011-12-07
Release date:2012-03-14
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.
Science, 335, 2012
3V0C
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BU of 3v0c by Molmil
4.3 angstrom crystal structure of an inactive BoNT/A (E224Q/R363A/Y366F)
Descriptor: BoNT/A, ZINC ION
Authors:Gu, S, Rumpel, S, Zhou, J, Strotmeier, J, Bigalke, H, Perry, K, Shoemaker, C.B, Rummel, A, Jin, R.
Deposit date:2011-12-07
Release date:2012-03-14
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.
Science, 335, 2012
5C54
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BU of 5c54 by Molmil
Crystal structure of a novel N-acetylneuraminic acid lyase from Corynebacterium glutamicum
Descriptor: Dihydrodipicolinate synthase/N-acetylneuraminate lyase, GLYCEROL
Authors:Shen, Y, Zhou, J, Xie, J.
Deposit date:2015-06-19
Release date:2016-06-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Crystal structure of a novel N-acetylneuraminic acid lyase from Corynebacterium glutamicum
To Be Published
5C55
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BU of 5c55 by Molmil
Crystal structure of the Y138F mutant of C.glutamicum N-acetylneuraminic acid lyase in complex with pyruvate
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Dihydrodipicolinate synthase/N-acetylneuraminate lyase, ...
Authors:Shen, Y, Zhou, J, Xie, J.
Deposit date:2015-06-19
Release date:2016-06-22
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the Y138F mutant of C.glutamicum N-acetylneuraminic acid lyase in complex with pyruvate
To Be Published
7RST
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BU of 7rst by Molmil
The Crystal Structure of Recombinant Chloroperoxidase Expressed in Aspergillus niger
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chloroperoxidase, ...
Authors:Tang, X, Venkadesh, S, Zhou, J, Rosen, B, Wang, X.
Deposit date:2021-08-11
Release date:2022-08-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:The Crystal Structure of Recombinant Chloroperoxidase Expressed in Aspergillus niger
To Be Published
4QY0
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BU of 4qy0 by Molmil
Structure of H10 from human-infecting H10N8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin
Authors:Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
Deposit date:2014-07-23
Release date:2015-01-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4QY2
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BU of 4qy2 by Molmil
Structure of H10 from human-infecting H10N8 virus in complex with human receptor analog
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, hemagglutinin
Authors:Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
Deposit date:2014-07-23
Release date:2015-01-28
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
3V64
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BU of 3v64 by Molmil
Crystal Structure of agrin and LRP4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Low-density lipoprotein receptor-related protein 4, ...
Authors:Zong, Y, Zhang, B, Gu, S, Lee, K, Zhou, J, Yao, G, Figueiedo, D, Perry, K, Mei, L, Jin, R.
Deposit date:2011-12-18
Release date:2012-04-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis of agrin-LRP4-MuSK signaling.
Genes Dev., 26, 2012
5GCN
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BU of 5gcn by Molmil
CATALYTIC DOMAIN OF TETRAHYMENA GCN5 HISTONE ACETYLTRANSFERASE IN COMPLEX WITH COENZYME A
Descriptor: COENZYME A, HISTONE ACETYLTRANSFERASE GCN5
Authors:Lin, Y, Fletcher, C.M, Zhou, J, Allis, C.D, Wagner, G.
Deposit date:1999-03-24
Release date:1999-07-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the catalytic domain of GCN5 histone acetyltransferase bound to coenzyme A
Nature, 400, 1999
5H2T
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BU of 5h2t by Molmil
Structure of trehalose synthase
Descriptor: Trehalose synthase
Authors:Wang, D, Huang, H, Zhou, J, Jiang, L.
Deposit date:2016-10-18
Release date:2017-10-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.796 Å)
Cite:Structure of trehalose synthase
To Be Published
5H5X
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BU of 5h5x by Molmil
Crystal structure of NADH bound carbonyl reductase from Streptomyces coelicolor
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ISOPROPYL ALCOHOL, MAGNESIUM ION, ...
Authors:Kong, X.-D, Xu, J.-H, Zhou, J.
Deposit date:2016-11-10
Release date:2017-05-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of NADH bound carbonyl reductase from Streptomyces coelicolor
To Be Published
5HSI
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BU of 5hsi by Molmil
Crystal structure of tyrosine decarboxylase at 1.73 Angstroms resolution
Descriptor: MAGNESIUM ION, Putative decarboxylase
Authors:Ni, Y, Zhou, J, Zhu, H, Zhang, K.
Deposit date:2016-01-25
Release date:2016-09-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.732 Å)
Cite:Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding
Sci Rep, 6, 2016
4P5A
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BU of 4p5a by Molmil
Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br UMP
Descriptor: 5-BROMO-URIDINE-5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, Thymidylate synthase ThyX
Authors:Li, Y, Chen, W, Li, J, Xia, Z, Deng, Z, Zhou, J.
Deposit date:2014-03-15
Release date:2015-12-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi with 5-Br UMP
To Be Published
4MYD
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1.37 Angstrom Crystal Structure of E. Coli 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (MenH) in complex with SHCHC
Descriptor: 2-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
Authors:Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z.
Deposit date:2013-09-27
Release date:2014-04-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.374 Å)
Cite:Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad.
J.Biol.Chem., 289, 2014
4MXD
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1.45 angstronm crystal structure of E.coli 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (MenH)
Descriptor: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z.
Deposit date:2013-09-26
Release date:2014-04-23
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad.
J.Biol.Chem., 289, 2014

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