8HKS

Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Pamiparib(BGB-290)

Summary for 8HKS

• Entry DOI: 10.2210/pdb8hks/pdb
• Descriptor: Poly [ADP-ribose] polymerase 2, GLYCEROL, (2R)-14-fluoro-2-methyl-6,9,10,19-tetrazapentacyclo[14.2.1.02,6.08,18.012,17]nonadeca-1(18),8,12(17),13,15-pentaen-11-one, ... (4 entities in total)
• Functional Keywords: dna adp-ribosyltransferase 2, parp2, pamiparib, bgb-290, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 162162.03

Authors

Wang, X.Y.,Zhou, J.,Xu, B.L. (deposition date: 2022-11-28, release date: 2024-05-01)

• Primary citation: Wang, X.Y.,Zhou, J.,Xu, B.L.; Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Pamiparib; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)