Crystal Structure of agrin and LRP4

Summary for 3V64

DescriptorLow-density lipoprotein receptor-related protein 4, agrin, N-ACETYL-D-GLUCOSAMINE, ... (6 entities in total)
Functional Keywordsbeta propeller, laminin-g, signaling, protein binding
Biological sourceRattus norvegicus (rat)
Cellular locationCell junction, synapse  Q9QYP1
Membrane ; Single-pass type I membrane protein  P25304
Total number of polymer chains4
Total molecular weight121718.88
Zong, Y.,Zhang, B.,Gu, S.,Lee, K.,Zhou, J.,Yao, G.,Figueiedo, D.,Perry, K.,Mei, L.,Jin, R. (deposition date: 2011-12-18, release date: 2012-04-25, Last modification date: 2017-03-01)
Primary citation
Zong, Y.,Zhang, B.,Gu, S.,Lee, K.,Zhou, J.,Yao, G.,Figueiredo, D.,Perry, K.,Mei, L.,Jin, R.
Structural basis of agrin-LRP4-MuSK signaling.
Genes Dev., 26:247-258, 2012
PubMed: 22302937 (PDB entries with the same primary citation)
DOI: 10.1101/gad.180885.111
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers0.277160.2%1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload