3V0C

4.3 angstrom crystal structure of an inactive BoNT/A (E224Q/R363A/Y366F)

Summary for 3V0C

DescriptorBoNT/A, ZINC ION (2 entities in total)
Functional Keywordsbotulinum neurotoxin, toxin, neurotoxin associated protein, progenitor toxin complex, vhh bound interlocked complex, ntnha
Biological sourceClostridium botulinum
Total number of polymer chains1
Total molecular weight151264.13
Authors
Gu, S.,Rumpel, S.,Zhou, J.,Strotmeier, J.,Bigalke, H.,Perry, K.,Shoemaker, C.B.,Rummel, A.,Jin, R. (deposition date: 2011-12-07, release date: 2012-03-14)
Primary citation
Gu, S.,Rumpel, S.,Zhou, J.,Strotmeier, J.,Bigalke, H.,Perry, K.,Shoemaker, C.B.,Rummel, A.,Jin, R.
Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.
Science, 335:977-981, 2012
PubMed: 22363010 (PDB entries with the same primary citation)
DOI: 10.1126/science.1214270
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (4.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.330576.9%6.6%2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload