2HZ6
The crystal structure of human IRE1-alpha luminal domain
Summary for 2HZ6
| Entry DOI | 10.2210/pdb2hz6/pdb |
| Descriptor | Endoplasmic reticulum to nucleus signalling 1 isoform 1 variant (1 entity in total) |
| Functional Keywords | triangular beta-sheet cluster, signaling protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 41191.55 |
| Authors | Kaufman, R.J.,Xu, Z.,Zhou, J. (deposition date: 2006-08-08, release date: 2006-08-29, Last modification date: 2024-02-21) |
| Primary citation | Zhou, J.,Liu, C.Y.,Back, S.H.,Clark, R.L.,Peisach, D.,Xu, Z.,Kaufman, R.J. The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response. Proc.Natl.Acad.Sci.Usa, 103:14343-14348, 2006 Cited by PubMed: 16973740DOI: 10.1073/pnas.0606480103 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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