2HZ6
The crystal structure of human IRE1-alpha luminal domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Endoplasmic reticulum to nucleus signalling 1 isoform 1 variant | polymer | 369 | 41191.5 | 1 | UniProt (Q59EE2) UniProt (by SIFTS) (O75460) In PDB | Homo sapiens (human) |
Sequence modifications
A: 24 - 390 (UniProt: Q59EE2)
| PDB | External Database | Details |
|---|---|---|
| Gly 22 | - | cloning artifact |
| Ser 23 | - | cloning artifact |
| Ser 148 | Cys 177 | engineered mutation |
| Ser 332 | Cys 361 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41191.5 | |
| All* | Total formula weight | 41191.5 |
