6NKO
 
 | | Crystal structure of ForH | | 分子名称: | ForH | | 著者 | Zheng, J, Irani, S, Zhang, Y. | | 登録日 | 2019-01-07 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.403 Å) | | 主引用文献 | Identification of the Formycin A Biosynthetic Gene Cluster from Streptomyces kaniharaensis Illustrates the Interplay between Biological Pyrazolopyrimidine Formation and de Novo Purine Biosynthesis.
J. Am. Chem. Soc., 141, 2019
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7YL2
 | | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004 | | 分子名称: | Bromodomain-containing protein 4, GLYCEROL, N-(1-ethyl-2-oxidanylidene-3H-indol-5-yl)cyclohexanesulfonamide, ... | | 著者 | Huang, Y, Wei, A, Dong, R, Xu, H, Zhang, C, Chen, Z, Li, J, Wu, X, Zhang, Y, Xu, Y. | | 登録日 | 2022-07-25 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004
To Be Published
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8K5P
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4GFU
 | | PTPN18 in complex with HER2-pY1248 phosphor-peptides | | 分子名称: | HER2-pY1248 phosphor-peptide, Tyrosine-protein phosphatase non-receptor type 18 | | 著者 | Wang, H.M, Yang, F, Du, Y.J, Yang, D.X, Zhang, Y, Yu, X, Sun, J.P. | | 登録日 | 2012-08-04 | | 公開日 | 2013-08-07 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | PTPN18-HER2 peptides
To be Published
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7YE1
 | | The cryo-EM structure of C. crescentus GcrA-TACup | | 分子名称: | Cell cycle regulatory protein GcrA, DNA (57-MER)-non template, DNA (57-MER)-template, ... | | 著者 | Wu, X.X, Zhang, Y. | | 登録日 | 2022-07-05 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structures of Caulobacter crescentus transcription activation complex with an essential cell cycle regulator GcrA
Nucleic Acids Res., 2023
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7YE2
 | | The cryo-EM structure of C. crescentus GcrA-TACdown | | 分子名称: | Cell cycle regulatory protein GcrA, DNA (90-MER)-non template, DNA (90-MER)-template, ... | | 著者 | Wu, X.X, Zhang, Y. | | 登録日 | 2022-07-05 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structures of Caulobacter crescentus transcription activation complex with an essential cell cycle regulator GcrA
Nucleic Acids Res., 2023
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8KCB
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2ITK
 | | human Pin1 bound to D-PEPTIDE | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, D-Peptide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Noel, J.P, Zhang, Y. | | 登録日 | 2006-10-19 | | 公開日 | 2007-05-22 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structural basis for high-affinity peptide inhibition of human Pin1.
Acs Chem.Biol., 2, 2007
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3NR9
 | | Structure of human CDC2-like kinase 2 (CLK2) | | 分子名称: | (5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one, Dual specificity protein kinase CLK2 | | 著者 | Chaikuad, A, Savitsky, P, Krojer, T, Muniz, J.R.C, Filippakopoulos, P, Rellos, P, Keates, T, Fedorov, O, Pike, A.C.W, Eswaran, J, Berridge, G, Phillips, C, Zhang, Y, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2010-06-30 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Structure of human CDC2-like kinase 2 (CLK2)
To be Published
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2I0L
 | | X-ray crystal structure of Sap97 PDZ2 bound to the C-terminal peptide of HPV18 E6. | | 分子名称: | Disks large homolog 1, peptide E6 | | 著者 | Chen, X.S, Zhang, Y, Dasgupta, J, Banks, L, Thomas, M. | | 登録日 | 2006-08-10 | | 公開日 | 2007-02-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Structures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein.
J.Virol., 81, 2007
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2I04
 | | X-ray crystal structure of MAGI-1 PDZ1 bound to the C-terminal peptide of HPV18 E6 | | 分子名称: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, SULFATE ION, ... | | 著者 | Chen, X.S, Zhang, Y, Dasgupta, J, Banks, L, Thomas, M. | | 登録日 | 2006-08-09 | | 公開日 | 2007-02-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein.
J.Virol., 81, 2007
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4GFV
 | | PTPN18 in complex with HER2-pY1196 phosphor-peptides | | 分子名称: | HER2-pY1196 phosphor-peptide, Tyrosine-protein phosphatase non-receptor type 18 | | 著者 | Wang, H.M, Yang, F, Du, Y.J, Yang, D.X, Zhang, Y, Yu, X, Sun, J.P. | | 登録日 | 2012-08-04 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.095 Å) | | 主引用文献 | PTPN18-HER2 peptides
To be Published
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4CKH
 | | Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy | | 分子名称: | ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 | | 著者 | Pang, X.Y, Fan, J, Zhang, Y, Zhang, K, Gao, B.Q, Ma, J, Li, J, Deng, Y.C, Zhou, Q.J, Hsu, V, Sun, F. | | 登録日 | 2014-01-06 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (17 Å) | | 主引用文献 | A Ph Domain in Acap1 Possesses Key Features of the Bar Domain in Promoting Membrane Curvature.
Dev.Cell, 31, 2014
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4CKG
 | | Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy | | 分子名称: | ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 | | 著者 | Pang, X.Y, Fan, J, Zhang, Y, Zhang, K, Gao, B.Q, Ma, J, Li, J, Deng, Y.C, Zhou, Q.J, Hsu, V, Sun, F. | | 登録日 | 2014-01-06 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (15 Å) | | 主引用文献 | A Ph Domain in Acap1 Possesses Key Features of the Bar Domain in Promoting Membrane Curvature.
Dev.Cell, 31, 2014
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6AZ3
 | | Cryo-EM structure of of the large subunit of Leishmania ribosome bound to paromomycin | | 分子名称: | 60S ribosomal protein L10, putative, 60S ribosomal protein L11 (L5, ... | | 著者 | Shalev-Benami, M, Zhang, Y, Rozenberg, H, Nobe, Y, Taoka, M, Matzov, D, Zimmerman, E, Bashan, A, Isobe, T, Jaffe, C.L, Yonath, A, Skiniotis, G. | | 登録日 | 2017-09-09 | | 公開日 | 2017-12-06 | | 最終更新日 | 2022-04-13 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.
Nat Commun, 8, 2017
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4IMJ
 | | Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine-tune the Phosphatase Activity of Ssu72 | | 分子名称: | CG14216, CTD, PHOSPHATE ION, ... | | 著者 | Luo, Y, Yogesha, S.D, Zhang, Y. | | 登録日 | 2013-01-03 | | 公開日 | 2013-08-07 | | 最終更新日 | 2013-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Novel Modifications on C-terminal Domain of RNA Polymerase II Can Fine-tune the Phosphatase Activity of Ssu72.
Acs Chem.Biol., 8, 2013
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6BM0
 | | Cryo-EM structure of human CPSF-160-WDR33 complex at 3.8 A resolution | | 分子名称: | Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33 | | 著者 | Sun, Y, Zhang, Y, Hamilton, K, Walz, T, Tong, L. | | 登録日 | 2017-11-12 | | 公開日 | 2017-11-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Molecular basis for the recognition of the human AAUAAA polyadenylation signal.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2I0I
 | | X-ray crystal structure of Sap97 PDZ3 bound to the C-terminal peptide of HPV18 E6 | | 分子名称: | Disks large homolog 1, peptide E6 | | 著者 | Chen, X.S, Zhang, Y, Dasgupta, J, Banks, L, Thomas, M. | | 登録日 | 2006-08-10 | | 公開日 | 2007-02-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein.
J.Virol., 81, 2007
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4IMI
 | | Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine- tune the Phosphatase Activity of Ssu72. | | 分子名称: | CG14216, CTD, PHOSPHATE ION, ... | | 著者 | Luo, Y, Yogesha, S.D, Zhang, Y. | | 登録日 | 2013-01-03 | | 公開日 | 2013-08-07 | | 最終更新日 | 2013-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Novel Modifications on C-terminal Domain of RNA Polymerase II Can Fine-tune the Phosphatase Activity of Ssu72.
Acs Chem.Biol., 8, 2013
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6BLY
 | | Cryo-EM structure of human CPSF-160-WDR33 complex at 3.36A resolution | | 分子名称: | Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33 | | 著者 | Sun, Y, Zhang, Y, Hamilton, K, Walz, T, Tong, L. | | 登録日 | 2017-11-12 | | 公開日 | 2017-11-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | | 主引用文献 | Molecular basis for the recognition of the human AAUAAA polyadenylation signal.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4N1Z
 | | Crystal Structure of Human Farnesyl Diphosphate Synthase in Complex with BPH-1222 | | 分子名称: | Farnesyl pyrophosphate synthase, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Liu, Y.L, Xia, Y, Zhang, Y, Verma, I, Oldfield, E. | | 登録日 | 2013-10-04 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin.
Sci Transl Med, 6, 2014
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2GQD
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2H2M
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2JOA
 | | HtrA1 bound to an optimized peptide: NMR assignment of PDZ domain and ligand resonances | | 分子名称: | Peptide H1-C1, Serine protease HTRA1 | | 著者 | Runyon, S.T, Zhang, Y, Appleton, B.A, Sazinksy, S.L, Wu, P, Pan, B, Wiesmann, C, Skelton, N.J, Sidhu, S.S. | | 登録日 | 2007-03-01 | | 公開日 | 2007-11-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3
Protein Sci., 16, 2007
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2L9S
 | | Solution structure of Pf1 SID1-mSin3A PAH2 Complex | | 分子名称: | PHD finger protein 12, Paired amphipathic helix protein Sin3a | | 著者 | Senthil Kumar, G, Xie, T, Zhang, Y, Radhakrishnan, I. | | 登録日 | 2011-02-23 | | 公開日 | 2011-05-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the mSin3A PAH2-Pf1 SID1 Complex: A Mad1/Mxd1-Like Interaction Disrupted by MRG15 in the Rpd3S/Sin3S Complex.
J.Mol.Biol., 408, 2011
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