6AZ3

Cryo-EM structure of of the large subunit of Leishmania ribosome bound to paromomycin

This is a non-PDB format compatible entry.

Summary for 6AZ3

• Entry DOI: 10.2210/pdb6az3/pdb
• Related: 6AZ1
• EMDB information: 7024 7025
• Descriptor: ribosomal protein uL2, 60S ribosomal protein L23, putative, Probable 60S ribosomal protein L14, ... (53 entities in total)
• Functional Keywords: leishmania, ribosome, aminoglycoside, paromomycin, ribosome-antibiotic complex, ribosome/antibiotic
• Biological source: Leishmania donovani; More
• Total number of polymer chains: 50
• Total formula weight: 2119489.92

Authors

Shalev-Benami, M.,Zhang, Y.,Rozenberg, H.,Nobe, Y.,Taoka, M.,Matzov, D.,Zimmerman, E.,Bashan, A.,Isobe, T.,Jaffe, C.L.,Yonath, A.,Skiniotis, G. (deposition date: 2017-09-09, release date: 2017-12-06, Last modification date: 2022-04-13)

• Primary citation: Shalev-Benami, M.,Zhang, Y.,Rozenberg, H.,Nobe, Y.,Taoka, M.,Matzov, D.,Zimmerman, E.,Bashan, A.,Isobe, T.,Jaffe, C.L.,Yonath, A.,Skiniotis, G.; Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.; Nat Commun, 8:1589-1589, 2017; PubMed: 29150609; DOI: 10.1038/s41467-017-01664-4

Experimental method

ELECTRON MICROSCOPY (2.5 Å)