2I0L
X-ray crystal structure of Sap97 PDZ2 bound to the C-terminal peptide of HPV18 E6.
Summary for 2I0L
| Entry DOI | 10.2210/pdb2i0l/pdb |
| Descriptor | Disks large homolog 1, peptide E6 (3 entities in total) |
| Functional Keywords | sap97 pdz2, hpv18 e6, tumor suppressor, carcinoma, peptide binding protein |
| Biological source | Rattus norvegicus (Norway rat) More |
| Cellular location | Membrane; Peripheral membrane protein (By similarity): Q62696 Host nucleus matrix (By similarity): P06463 |
| Total number of polymer chains | 4 |
| Total formula weight | 19580.40 |
| Authors | Chen, X.S.,Zhang, Y.,Dasgupta, J.,Banks, L.,Thomas, M. (deposition date: 2006-08-10, release date: 2007-02-20, Last modification date: 2024-02-21) |
| Primary citation | Zhang, Y.,Dasgupta, J.,Ma, R.Z.,Banks, L.,Thomas, M.,Chen, X.S. Structures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein. J.Virol., 81:3618-3626, 2007 Cited by PubMed: 17267502DOI: 10.1128/JVI.02044-06 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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