7YL2

Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004

Summary for 7YL2

• Entry DOI: 10.2210/pdb7yl2/pdb
• Descriptor: Bromodomain-containing protein 4, N-(1-ethyl-2-oxidanylidene-3H-indol-5-yl)cyclohexanesulfonamide, GLYCEROL, ... (5 entities in total)
• Functional Keywords: brd4(1), bromodomain, inhibitor, antitumor protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 17243.85

Authors

Huang, Y.,Wei, A.,Dong, R.,Xu, H.,Zhang, C.,Chen, Z.,Li, J.,Wu, X.,Zhang, Y.,Xu, Y. (deposition date: 2022-07-25, release date: 2023-07-26, Last modification date: 2026-03-04)

• Primary citation: Huang, Y.,Wei, A.,Dong, R.,Xu, H.,Zhang, C.,Chen, Z.,Li, J.,Wu, X.,Zhang, Y.,Xu, Y.; Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.62 Å)