2ITK

human Pin1 bound to D-PEPTIDE

Summary for 2ITK

• Entry DOI: 10.2210/pdb2itk/pdb
• Related: 1F8A 1PIN 2ITI
• Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, D-Peptide, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... (4 entities in total)
• Functional Keywords: pin1, isomerase, ww domain, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q13526
• Total number of polymer chains: 2
• Total formula weight: 19685.78

Authors

Noel, J.P.,Zhang, Y. (deposition date: 2006-10-19, release date: 2007-05-22, Last modification date: 2023-11-15)

• Primary citation: Zhang, Y.,Daum, S.,Wildemann, D.,Zhou, X.Z.,Verdecia, M.A.,Bowman, M.E.,Lucke, C.,Hunter, T.,Lu, K.P.,Fischer, G.,Noel, J.P.; Structural basis for high-affinity peptide inhibition of human Pin1.; Acs Chem.Biol., 2:320-328, 2007; PubMed: 17518432; DOI: 10.1021/cb7000044

Experimental method

X-RAY DIFFRACTION (1.45 Å)