7BZC
 
 | | Crystal structure of plant sesterterpene synthase AtTPS18 complexed with farnesyl thiolodiphosphate (FSPP) | | Descriptor: | MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, Terpenoid synthase 18 | | Authors: | Li, J.X, Wang, G.D, Zhang, P. | | Deposit date: | 2020-04-27 | | Release date: | 2020-09-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.303 Å) | | Cite: | Molecular Basis for Sesterterpene Diversity Produced by Plant Terpene Synthases.
Plant Commun., 1, 2020
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2M6B
 | | Structure of full-length transmembrane domains of human glycine receptor alpha1 monomer subunit | | Descriptor: | Full-Length Transmembrane Domains of Human Glycine Receptor alpha1 Subunit | | Authors: | Mowrey, D, Cui, T, Jia, Y, Ma, D, Makhov, A.M, Zhang, P, Tang, P, Xu, Y. | | Deposit date: | 2013-03-28 | | Release date: | 2013-09-04 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Open-Channel Structures of the Human Glycine Receptor alpha 1 Full-Length Transmembrane Domain.
Structure, 21, 2013
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5UOT
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7CSG
 | | AtPrR2 in apo form | | Descriptor: | Pinoresinol reductase 2 | | Authors: | Shao, K, Zhang, P. | | Deposit date: | 2020-08-14 | | Release date: | 2021-06-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.99689388 Å) | | Cite: | Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases.
Nat Commun, 12, 2021
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8Y7E
 | | Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U12 snRNP part | | Descriptor: | PHD finger-like domain-containing protein 5A, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... | | Authors: | Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R. | | Deposit date: | 2024-02-04 | | Release date: | 2024-03-13 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.66 Å) | | Cite: | Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Science, 383, 2024
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3DW8
 | | Structure of a Protein Phosphatase 2A Holoenzyme with B55 subunit | | Descriptor: | MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... | | Authors: | Xu, Y, Chen, Y, Zhang, P, Jeffrey, P.D, Shi, Y. | | Deposit date: | 2008-07-21 | | Release date: | 2008-10-07 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structure of a protein phosphatase 2A holoenzyme: insights into B55-mediated Tau dephosphorylation.
Mol.Cell, 31, 2008
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5V6I
 | | Glycan binding protein Y3 from mushroom Coprinus comatus possesses anti-leukemic activity - Pt derivative | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHLORIDE ION, PLATINUM (II) ION, ... | | Authors: | Li, K, Zhang, P, Gang, Y, Xia, C, Polston, J.E, Li, G, Li, S, Lin, Z, Yang, L.-J, Bruner, S.D, Ding, Y. | | Deposit date: | 2017-03-16 | | Release date: | 2017-08-16 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Cytotoxic protein from the mushroom Coprinus comatus possesses a unique mode for glycan binding and specificity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6LPV
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7AX3
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8FAC
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7CS2
 | | Apo structure of dimeric IiPLR1 | | Descriptor: | Pinoresinol-lariciresinol reductase | | Authors: | Shao, K, Zhang, P. | | Deposit date: | 2020-08-14 | | Release date: | 2021-06-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.68800473 Å) | | Cite: | Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases.
Nat Commun, 12, 2021
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7CSH
 | | AtPrR2 with NADP+ and (+)pinoresinol | | Descriptor: | 4-[(3S,3aR,6S,6aR)-6-(3-methoxy-4-oxidanyl-phenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxy-phenol, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pinoresinol reductase 2 | | Authors: | Shao, K, Zhang, P. | | Deposit date: | 2020-08-14 | | Release date: | 2021-06-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.590775 Å) | | Cite: | Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases.
Nat Commun, 12, 2021
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5E8H
 | | Crystal structure of geranylfarnesyl pyrophosphate synthases 2 from Arabidopsis thaliana | | Descriptor: | Geranylgeranyl pyrophosphate synthase 3, chloroplastic | | Authors: | Wang, C, Chen, Q, Wang, G, Zhang, P. | | Deposit date: | 2015-10-14 | | Release date: | 2015-11-11 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants.
Mol Plant, 9, 2016
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3E9G
 | | Crystal structure long-form (residue1-124) of Eaf3 chromo domain | | Descriptor: | Chromatin modification-related protein EAF3 | | Authors: | Sun, B, Hong, J, Zhang, P, Lin, D, Ding, J. | | Deposit date: | 2008-08-22 | | Release date: | 2008-11-04 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular Basis of the Interaction of Saccharomyces cerevisiae Eaf3 Chromo Domain with Methylated H3K36
J.Biol.Chem., 283, 2008
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5V6J
 | | Glycan binding protein Y3 from mushroom Coprinus comatus possesses anti-leukemic activity | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, TMV resistance protein Y3 | | Authors: | Li, K, Zhang, P, Gang, Y, Xia, C, Polston, J.E, Li, G, Li, S, Lin, Z, Yang, L.-J, Bruner, S.D, Ding, Y. | | Deposit date: | 2017-03-16 | | Release date: | 2017-08-16 | | Last modified: | 2017-09-06 | | Method: | X-RAY DIFFRACTION (1.18 Å) | | Cite: | Cytotoxic protein from the mushroom Coprinus comatus possesses a unique mode for glycan binding and specificity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8FY0
 | | E3:PROTAC:target ternary complex structure (VCB/753b/BCL-xL) | | Descriptor: | Bcl-2-like protein 1, CACODYLIC ACID, Elongin-B, ... | | Authors: | Olsen, S.K, Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D. | | Deposit date: | 2023-01-25 | | Release date: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL.
Nat Commun, 15, 2024
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8FY1
 | | E3:PROTAC:target ternary complex structure (VCB/753b/BCL-2) | | Descriptor: | Apoptosis regulator Bcl-2, Elongin-B, Elongin-C, ... | | Authors: | Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D, Olsen, S.K. | | Deposit date: | 2023-01-25 | | Release date: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL.
Nat Commun, 15, 2024
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8FY2
 | | E3:PROTAC:target ternary complex structure (VCB/WH244/BCL-2) | | Descriptor: | Apoptosis regulator Bcl-2, Elongin-B, Elongin-C, ... | | Authors: | Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Ruben, E, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D, Olsen, S.K. | | Deposit date: | 2023-01-25 | | Release date: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (2.98 Å) | | Cite: | Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL.
Nat Commun, 15, 2024
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5E8K
 | | Crystal structure of polyprenyl pyrophosphate synthase 2 from Arabidopsis thaliana | | Descriptor: | Geranylgeranyl pyrophosphate synthase 10, mitochondrial | | Authors: | Wang, C, Chen, Q, Fan, D, Li, J, Wang, G, Zhang, P. | | Deposit date: | 2015-10-14 | | Release date: | 2015-11-11 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.028 Å) | | Cite: | Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants.
Mol Plant, 9, 2016
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3E9F
 | | Crystal structure short-form (residue1-113) of Eaf3 chromo domain | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Chromatin modification-related protein EAF3 | | Authors: | Sun, B, Hong, J, Zhang, P, Lin, D, Ding, J. | | Deposit date: | 2008-08-22 | | Release date: | 2008-11-04 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Molecular Basis of the Interaction of Saccharomyces cerevisiae Eaf3 Chromo Domain with Methylated H3K36
J.Biol.Chem., 283, 2008
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7ASL
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7ASH
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7EGK
 | | Bicarbonate transporter complex SbtA-SbtB bound to AMP | | Descriptor: | ADENOSINE MONOPHOSPHATE, Membrane-associated protein SbtB, SODIUM ION, ... | | Authors: | Fang, S, Huang, X, Zhang, X, Zhang, P. | | Deposit date: | 2021-03-24 | | Release date: | 2021-05-26 | | Last modified: | 2021-06-16 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Molecular mechanism underlying transport and allosteric inhibition of bicarbonate transporter SbtA.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7E1B
 | | Crystal structure of VbrR-DNA complex | | Descriptor: | DNA (26-MER), DNA-binding response regulator | | Authors: | Hong, S, Zhang, X, Zhang, P. | | Deposit date: | 2021-02-01 | | Release date: | 2022-02-09 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (4.587 Å) | | Cite: | Structural basis of phosphorylation-induced activation of the response regulator VbrR.
Acta Biochim.Biophys.Sin., 2023
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3S32
 | | Crystal structure of Ash2L N-terminal domain | | Descriptor: | Set1/Ash2 histone methyltransferase complex subunit ASH2, ZINC ION | | Authors: | Sarvan, S, Avdic, V, Tremblay, V, Chaturvedi, C.-P, Zhang, P, Lanouette, S, Blais, A, Brunzelle, J.S, Brand, M, Couture, J.-F. | | Deposit date: | 2011-05-17 | | Release date: | 2011-06-08 | | Last modified: | 2012-01-11 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal structure of the trithorax group protein ASH2L reveals a forkhead-like DNA binding domain.
Nat.Struct.Mol.Biol., 18, 2011
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