3S32

Crystal structure of Ash2L N-terminal domain

Summary for 3S32

Entry DOI	10.2210/pdb3s32/pdb
Descriptor	Set1/Ash2 histone methyltransferase complex subunit ASH2, ZINC ION (3 entities in total)
Functional Keywords	histone, chromatin, trithorax, helix-wing-helix, c4-zinc finger, trithorax group protein, myeloid lymphoma leukemia protein, nucleus, transcription
Biological source	Homo sapiens (human)
Cellular location	Nucleus (Probable): Q9UBL3
Total number of polymer chains	1
Total formula weight	22104.85
Authors	Sarvan, S.,Avdic, V.,Tremblay, V.,Chaturvedi, C.-P.,Zhang, P.,Lanouette, S.,Blais, A.,Brunzelle, J.S.,Brand, M.,Couture, J.-F. (deposition date: 2011-05-17, release date: 2011-06-08, Last modification date: 2012-01-11)
Primary citation	Sarvan, S.,Avdic, V.,Tremblay, V.,Chaturvedi, C.P.,Zhang, P.,Lanouette, S.,Blais, A.,Brunzelle, J.S.,Brand, M.,Couture, J.F. Crystal structure of the trithorax group protein ASH2L reveals a forkhead-like DNA binding domain. Nat.Struct.Mol.Biol., 18:857-859, 2011 Cited by PubMed: 21642971 DOI: 10.1038/nsmb.2093 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation