5UOT
CryoEM structure of the helical assembly of full length MxB
This is a non-PDB format compatible entry.
Summary for 5UOT
| Entry DOI | 10.2210/pdb5uot/pdb |
| EMDB information | 8577 |
| Descriptor | Interferon-induced GTP-binding protein Mx2 (1 entity in total) |
| Functional Keywords | cryoem, mx2, mxb, assembly, interferon, hiv-1, dynamin, helical reconstruction, molecular dynamic simulation, antiviral protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 62 |
| Total formula weight | 4400745.00 |
| Authors | Perilla, J.R.,Alvarez, F.J.D.,Zhang, P.,Schulten, K. (deposition date: 2017-02-01, release date: 2018-02-21, Last modification date: 2019-01-23) |
| Primary citation | Alvarez, F.J.D.,He, S.,Perilla, J.R.,Jang, S.,Schulten, K.,Engelman, A.N.,Scheres, S.H.W.,Zhang, P. CryoEM structure of MxB reveals a novel oligomerization interface critical for HIV restriction. Sci Adv, 3:e1701264-e1701264, 2017 Cited by PubMed: 28929138DOI: 10.1126/sciadv.1701264 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (4.6 Å) |
Structure validation
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