2JXN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jxn by Molmil](/molmil-images/mine/2jxn) | Solution Structure of S. cerevisiae PDCD5-like Protein Ymr074cp | Descriptor: | S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, Uncharacterized protein YMR074C | Authors: | Hong, J, Zhang, J, Liu, Z, Shi, Y, Wu, J. | Deposit date: | 2007-11-23 | Release date: | 2008-12-02 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Solution Structure and Dynamics of S. cerevisiae PDCD5-like Protein Ymr074cp Determined by Heteronuclear NMR Spectroscopy To be Published
|
|
2JXW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jxw by Molmil](/molmil-images/mine/2jxw) | |
7E6R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e6r by Molmil](/molmil-images/mine/7e6r) | Crystal structure of HCoV-NL63 3C-like protease,pH5.6 | Descriptor: | 3C-like proteinase | Authors: | Gao, H.X, Zhang, Y.T, Zhong, F.L, Zhou, X.L, Li, J, Zhang, J. | Deposit date: | 2021-02-23 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
|
|
7E6L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e6l by Molmil](/molmil-images/mine/7e6l) | Crystal structure of HCoV-NL63 3C-like protease,pH5.0 | Descriptor: | 3C-like proteinase | Authors: | Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J. | Deposit date: | 2021-02-22 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.78037143 Å) | Cite: | Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
|
|
7E6M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e6m by Molmil](/molmil-images/mine/7e6m) | Crystal structure of Human coronavirus NL63 3C-like protease | Descriptor: | 3C-like proteinase | Authors: | Gao, H.X, Zhang, Y.T, Zhong, F.L, Zhou, X.L, Li, J, Zhang, J. | Deposit date: | 2021-02-22 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.83445024 Å) | Cite: | Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
|
|
5JID
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jid by Molmil](/molmil-images/mine/5jid) | Crystal Structure of Human Transthyretin in Complex with Perfluorooctanoic acid (PFOA) | Descriptor: | SODIUM ION, Transthyretin, pentadecafluorooctanoic acid | Authors: | Begum, A, Zhang, J, Olofsson, A, Andersson, P, Sauer-Eriksson, A.E. | Deposit date: | 2016-04-22 | Release date: | 2016-10-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structure-Based Virtual Screening Protocol for in Silico Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin. Environ. Sci. Technol., 50, 2016
|
|
7E6N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e6n by Molmil](/molmil-images/mine/7e6n) | Crystal structure of HCoV-NL63 3C-like protease,pH5.2 | Descriptor: | 3C-like proteinase | Authors: | Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J. | Deposit date: | 2021-02-22 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8413 Å) | Cite: | Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
|
|
3NFC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nfc by Molmil](/molmil-images/mine/3nfc) | |
4K47
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4k47 by Molmil](/molmil-images/mine/4k47) | Structure of the Streptococcus pneumoniae leucyl-tRNA synthetase editing domain bound to a benzoxaborole-AMP adduct | Descriptor: | Leucine--tRNA ligase, SULFATE ION, [(1R,5R,6R,8S)-6-(6-aminopurin-9-yl)-3'-[(R)-oxidanyl(phenyl)methyl]spiro[2,4,7-trioxa-3-boranuidabicyclo[3.3.0]octane-3,9'-8-oxa-9-boranuidabicyclo[4.3.0]nona-1,3,5-triene]-8-yl]methyl dihydrogen phosphate | Authors: | Hu, Q.H, Liu, R.J, Fang, Z.P, Zhang, J, Ding, Y.Y, Tan, M, Wang, M, Pan, W, Zhou, H.C, Wang, E.D. | Deposit date: | 2013-04-12 | Release date: | 2013-09-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase Sci Rep, 3, 2013
|
|
1Z29
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z29 by Molmil](/molmil-images/mine/1z29) | Crystal Structures of SULT1A2 and SULT1A1*3: Implications in the bioactivation of N-hydroxy-2-acetylamino fluorine (OH-AAF) | Descriptor: | ACETIC ACID, ADENOSINE-3'-5'-DIPHOSPHATE, CALCIUM ION, ... | Authors: | Lu, J, Li, H, Liu, M.C, Zhang, J, Li, M, An, X, Chang, W. | Deposit date: | 2005-03-07 | Release date: | 2006-05-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of SULT1A2 and SULT1A1 *3: insights into the substrate inhibition and the role of Tyr149 in SULT1A2. Biochem.Biophys.Res.Commun., 396, 2010
|
|
4K48
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4k48 by Molmil](/molmil-images/mine/4k48) | Structure of the Streptococcus pneumoniae leucyl-tRNA synthetase editing domain | Descriptor: | Leucine--tRNA ligase | Authors: | Hu, Q.H, Liu, R.J, Fang, Z.P, Zhang, J, Ding, Y.Y, Tan, M, Wang, M, Pan, W, Zhou, H.C, Wang, E.D. | Deposit date: | 2013-04-12 | Release date: | 2013-09-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase Sci Rep, 3, 2013
|
|
2KBE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kbe by Molmil](/molmil-images/mine/2kbe) | |
2JWE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jwe by Molmil](/molmil-images/mine/2jwe) | Solution structure of the second PDZ domain from human zonula occludens-1: A dimeric form with 3D domain swapping | Descriptor: | Tight junction protein ZO-1 | Authors: | Ji, P, Wu, J.W, Zhang, J.H, Yang, Y.S, Wu, J.H, Shi, Y.Y. | Deposit date: | 2007-10-10 | Release date: | 2007-10-30 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the second PDZ domain of Zonula Occludens 1 Proteins, 79, 2011
|
|
4MSU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4msu by Molmil](/molmil-images/mine/4msu) | Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate | Descriptor: | 1,1,1,3,3,3-hexafluoro-2-{4-[4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... | Authors: | Ashton, K.S, Andrews, K.L, Bryan, M.C, Chen, J, Chen, K, Chen, M, Chmait, S, Croghan, M, Cupples, R, Fotsch, C, Helmering, J, Jordan, S.R, Kurzeja, R.J, Michelsen, K, Pennington, L.D, Poon, S.F, Sivits, G, Van, G, Vonderfecht, S.L, Wahl, R.C, Zhang, J, Lloyd, D.J, Hale, C, St Jean, D.J. | Deposit date: | 2013-09-18 | Release date: | 2014-03-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept. J.Med.Chem., 57, 2014
|
|
4GPO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4gpo by Molmil](/molmil-images/mine/4gpo) | |
1Z28
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z28 by Molmil](/molmil-images/mine/1z28) | Crystal Structures of SULT1A2 and SULT1A1*3: Implications in the bioactivation of N-hydroxy-2-acetylamino fluorine (OH-AAF) | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, Phenol-sulfating phenol sulfotransferase 1 | Authors: | Lu, J, Li, H, Liu, M.C, Zhang, J, Li, M, An, X, Chang, W. | Deposit date: | 2005-03-07 | Release date: | 2006-05-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of SULT1A2 and SULT1A1 *3: insights into the substrate inhibition and the role of Tyr149 in SULT1A2. Biochem.Biophys.Res.Commun., 396, 2010
|
|
2OIG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2oig by Molmil](/molmil-images/mine/2oig) | Crystal structure of RS21-C6 core segment and dm5CTP complex | Descriptor: | 2'-DEOXY-5-METHYLCYTIDINE 5'-(TETRAHYDROGEN TRIPHOSPHATE), RS21-C6 | Authors: | Wu, B, Liu, Y, Zhao, Q, Liao, S, Zhang, J, Bartlam, M, Chen, W, Rao, Z. | Deposit date: | 2007-01-11 | Release date: | 2007-03-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal Structure of RS21-C6, Involved in Nucleoside Triphosphate Pyrophosphohydrolysis J.Mol.Biol., 367, 2007
|
|
2A3R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2a3r by Molmil](/molmil-images/mine/2a3r) | Crystal Structure of Human Sulfotransferase SULT1A3 in Complex with Dopamine and 3-Phosphoadenosine 5-Phosphate | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, L-DOPAMINE, Monoamine-sulfating phenol sulfotransferase | Authors: | Lu, J.H, Li, H.T, Liu, M.C, Zhang, J.P, Li, M, An, X.M, Chang, W.R. | Deposit date: | 2005-06-26 | Release date: | 2005-08-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of human sulfotransferase SULT1A3 in complex with dopamine and 3'-phosphoadenosine 5'-phosphate Biochem.Biophys.Res.Commun., 335, 2005
|
|
2H7B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h7b by Molmil](/molmil-images/mine/2h7b) | Solution structure of the eTAFH domain from the human leukemia-associated fusion protein AML1-ETO | Descriptor: | Core-binding factor, ML1-ETO | Authors: | Plevin, M.J, Zhang, J, Guo, C, Roeder, R.G, Ikura, M. | Deposit date: | 2006-06-01 | Release date: | 2006-07-11 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain Proc.Natl.Acad.Sci.USA, 103, 2006
|
|
7WQH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wqh by Molmil](/molmil-images/mine/7wqh) | Crystal structure of HCoV-NL63 main protease with PF07304814 | Descriptor: | 3C-like proteinase, [(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl)carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate | Authors: | Zhong, F.L, Zhou, X.L, Lin, C, Zeng, P, Li, J, Zhang, J. | Deposit date: | 2022-01-25 | Release date: | 2022-08-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structural Basis of Main Proteases of Coronavirus Bound to Drug Candidate PF-07304814 J.Mol.Biol., 434, 2022
|
|
7WQJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wqj by Molmil](/molmil-images/mine/7wqj) | Crystal structure of MERS main protease in complex with PF07304814 | Descriptor: | 3C-like proteinase, [(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl)carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate | Authors: | Lin, C, Zhang, J, Li, J. | Deposit date: | 2022-01-25 | Release date: | 2022-08-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural Basis of Main Proteases of Coronavirus Bound to Drug Candidate PF-07304814 J.Mol.Biol., 434, 2022
|
|
2KU3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ku3 by Molmil](/molmil-images/mine/2ku3) | |
6K40
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6k40 by Molmil](/molmil-images/mine/6k40) | Crystal structure of alkyl hydroperoxide reductase from D. radiodurans R1 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alkyl hydroperoxide reductase AhpD, DI(HYDROXYETHYL)ETHER, ... | Authors: | Kim, M.-K, Zhang, J, Zhao, L. | Deposit date: | 2019-05-22 | Release date: | 2020-05-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Crystal structure of the AhpD-like protein DR1765 from Deinococcus radiodurans R1. Biochem.Biophys.Res.Commun., 529, 2020
|
|
2L43
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l43 by Molmil](/molmil-images/mine/2l43) | Structural basis for histone code recognition by BRPF2-PHD1 finger | Descriptor: | Histone H3.3,LINKER,Bromodomain-containing protein 1, ZINC ION | Authors: | Qin, S, Zhang, J, Wu, J, Shi, Y. | Deposit date: | 2010-10-01 | Release date: | 2011-08-31 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Recognition of unmodified histone H3 by the first PHD finger of Bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases MOZ and MORF To be Published
|
|
7DK0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dk0 by Molmil](/molmil-images/mine/7dk0) | Crystal structure of SARS-CoV-2 Spike RBD in complex with MW05 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MW05 heavy chain, MW05 light chain, ... | Authors: | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | Deposit date: | 2020-11-22 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.199 Å) | Cite: | Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction. Commun Biol, 5, 2022
|
|