3MEX

Crystal structure of MexR in oxidized state

Summary for 3MEX

Related1LNW 3ECH
DescriptorMultidrug resistance operon repressor (2 entities in total)
Functional Keywordsantibiotics resistance regulation, oxidative stress, thiol modification, dna-binding, transcription, transcription regulation
Biological sourcePseudomonas aeruginosa
Total number of polymer chains2
Total molecular weight32807.7
Authors
Chen, H.,Yi, C.,Zhang, J.,Zhang, W.,Yang, C.-G.,He, C. (deposition date: 2010-04-01, release date: 2010-07-28, Last modification date: 2011-07-13)
Primary citation
Chen, H.,Yi, C.,Zhang, J.,Zhang, W.,Ge, Z.,Yang, C.-G.,He, C.
Structural insight into the oxidation-sensing mechanism of the antibiotic resistance of regulator MexR
Embo Rep., 11:685-690, 2010
PubMed: 20616806 (PDB entries with the same primary citation)
DOI: 10.1038/embor.2010.96
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.258100.4%3.9%4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload