7Y71

SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7

Summary for 7Y71

Entry DOI	10.2210/pdb7y71/pdb
EMDB information	33650
Descriptor	Fab E7 light chain, Fab E7 heavy chain, Spike glycoprotein, ... (5 entities in total)
Functional Keywords	viral protein
Biological source	Homo sapiens More
Total number of polymer chains	5
Total formula weight	451908.01
Authors	Chia, W.N.,Tan, C.W.,Tan, A.W.K.,Young, B.,Starr, T.N.,Lopez, E.,Fibriansah, G.,Barr, J.,Cheng, S.,Yeoh, A.Y.Y.,Yap, W.C.,Lim, B.L.,Ng, T.S.,Sia, W.R.,Zhu, F.,Chen, S.,Zhang, J.,Greaney, A.J.,Chen, M.,Au, G.G.,Paradkar, P.,Peiris, M.,Chung, A.W.,Bloom, J.D.,Lye, D.,Lok, S.M.,Wang, L.F. (deposition date: 2022-06-21, release date: 2023-08-02, Last modification date: 2023-08-09)
Primary citation	Chia, W.N.,Tan, C.W.,Tan, A.W.K.,Young, B.,Starr, T.N.,Lopez, E.,Fibriansah, G.,Barr, J.,Cheng, S.,Yeoh, A.Y.,Yap, W.C.,Lim, B.L.,Ng, T.S.,Sia, W.R.,Zhu, F.,Chen, S.,Zhang, J.,Kwek, M.S.S.,Greaney, A.J.,Chen, M.,Au, G.G.,Paradkar, P.N.,Peiris, M.,Chung, A.W.,Bloom, J.D.,Lye, D.,Lok, S.,Wang, L.F. Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor. Sci Adv, 9:eade3470-eade3470, 2023 Cited by PubMed: 37494438 DOI: 10.1126/sciadv.ade3470 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.12 Å)

Structure validation