7Y71
SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | P | Fab E7 light chain | polymer | 219 | 23920.7 | 1 | Homo sapiens | ||
2 | O | Fab E7 heavy chain | polymer | 221 | 23339.2 | 1 | Homo sapiens | ||
3 | A, B, C | Spike glycoprotein | polymer | 1198 | 132860.2 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Homo sapiens (human) | S glycoprotein,E2,Peplomer protein |
4 | D, I, J, K, L... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 7 | In PDB GlyTouCan (G42666HT) | |||
5 | A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 14 | Chemie (NAG) |
Sequence modifications
A, B, C: 16 - 1213 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Ala 683 | Arg 683 | engineered mutation |
Ala 685 | Arg 685 | engineered mutation |
Pro 817 | Phe 817 | engineered mutation |
Pro 892 | Ala 892 | engineered mutation |
Pro 899 | Ala 899 | engineered mutation |
Pro 942 | Ala 942 | engineered mutation |
Pro 986 | Lys 986 | engineered mutation |
Pro 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 445840.3 | |
Branched | Number of molecules | 7 |
Total formula weight | 2970.8 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 3096.9 | |
All* | Total formula weight | 451908.0 |