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PDB: 320 件

1TB7
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Catalytic Domain Of Human Phosphodiesterase 4D In Complex With AMP
分子名称: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE MONOPHOSPHATE, ...
著者Zhang, K.Y.J, Card, G.L, Suzuki, Y, Artis, D.R, Fong, D, Gillette, S, Hsieh, D, Neiman, J, West, B.L, Zhang, C, Milburn, M.V, Kim, S.-H, Schlessinger, J, Bollag, G.
登録日2004-05-19
公開日2004-08-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases
Mol.Cell, 15, 2004
1TBF
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Catalytic Domain Of Human Phosphodiesterase 5A in Complex with Sildenafil
分子名称: 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, GLYCEROL, MAGNESIUM ION, ...
著者Zhang, K.Y.J, Card, G.L, Suzuki, Y, Artis, D.R, Fong, D, Gillette, S, Hsieh, D, Neiman, J, West, B.L, Zhang, C, Milburn, M.V, Kim, S.-H, Schlessinger, J, Bollag, G.
登録日2004-05-20
公開日2004-08-03
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases
Mol.Cell, 15, 2004
1T9R
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Catalytic Domain Of Human Phosphodiesterase 5A
分子名称: CITRIC ACID, PHOSPHATE ION, ZINC ION, ...
著者Zhang, K.Y.J, Card, G.L, Suzuki, Y, Artis, D.R, Fong, D, Gillette, S, Hsieh, D, Neiman, J, West, B.L, Zhang, C, Milburn, M.V, Kim, S.-H, Schlessinger, J, Bollag, G.
登録日2004-05-18
公開日2004-08-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases
Mol.Cell, 15, 2004
3J7X
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Capsid Expansion Mechanism Of Bacteriophage T7 Revealed By Multi-State Atomic Models Derived From Cryo-EM Reconstructions
分子名称: Major capsid protein 10A
著者Guo, F, Liu, Z, Fang, P.A, Zhang, Q, Wright, E.T, Wu, W, Zhang, C, Vago, F, Ren, Y, Jakata, J, Chiu, W, Serwer, P, Jiang, W.
登録日2014-08-12
公開日2014-10-15
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions.
Proc.Natl.Acad.Sci.USA, 111, 2014
3J7V
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Capsid Expansion Mechanism Of Bacteriophage T7 Revealed By Multi-State Atomic Models Derived From Cryo-EM Reconstructions
分子名称: Major capsid protein 10A
著者Guo, F, Liu, Z, Fang, P.A, Zhang, Q, Wright, E.T, Wu, W, Zhang, C, Vago, F, Ren, Y, Jakata, J, Chiu, W, Serwer, P, Jiang, W.
登録日2014-08-12
公開日2014-10-15
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions.
Proc.Natl.Acad.Sci.USA, 111, 2014
4ZXA
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BU of 4zxa by Molmil
Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD in complex with Cd2+ and 4-hydroxybenzonitrile
分子名称: 4-hydroxybenzonitrile, CADMIUM ION, Hydroquinone dioxygenase large subunit, ...
著者Liu, S, Su, T, Zhang, C, Gu, L.
登録日2015-05-20
公開日2015-09-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.488 Å)
主引用文献Crystal Structure of PnpCD, a Two-subunit Hydroquinone 1,2-Dioxygenase, Reveals a Novel Structural Class of Fe2+-dependent Dioxygenases.
J.Biol.Chem., 290, 2015
4ZXD
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Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD
分子名称: Hydroquinone dioxygenase large subunit, Hydroquinone dioxygenase small subunit
著者Liu, S, Su, T, Zhang, C, Gu, L.
登録日2015-05-20
公開日2015-09-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.052 Å)
主引用文献Crystal Structure of PnpCD, a Two-subunit Hydroquinone 1,2-Dioxygenase, Reveals a Novel Structural Class of Fe2+-dependent Dioxygenases.
J.Biol.Chem., 290, 2015
4ZXC
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Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD in complex with Fe3+
分子名称: FE (III) ION, Hydroquinone dioxygenase large subunit, Hydroquinone dioxygenase small subunit
著者Liu, S, Su, T, Zhang, C, Gu, L.
登録日2015-05-20
公開日2015-09-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal Structure of PnpCD, a Two-subunit Hydroquinone 1,2-Dioxygenase, Reveals a Novel Structural Class of Fe2+-dependent Dioxygenases.
J.Biol.Chem., 290, 2015
4QKX
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Structure of beta2 adrenoceptor bound to a covalent agonist and an engineered nanobody
分子名称: 4-[(1R)-1-hydroxy-2-({2-[3-methoxy-4-(2-sulfanylethoxy)phenyl]ethyl}amino)ethyl]benzene-1,2-diol, Beta-2 adrenergic receptor, R9 protein, ...
著者Weichert, D, Kruse, A.C, Manglik, A, Hiller, C, Zhang, C, Huebner, H, Kobilka, B.K, Gmeiner, P.
登録日2014-06-10
公開日2014-07-23
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Covalent agonists for studying G protein-coupled receptor activation.
Proc.Natl.Acad.Sci.USA, 111, 2014
3J7W
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BU of 3j7w by Molmil
Capsid Expansion Mechanism Of Bacteriophage T7 Revealed By Multi-State Atomic Models Derived From Cryo-EM Reconstructions
分子名称: Major capsid protein 10A
著者Guo, F, Liu, Z, Fang, P.A, Zhang, Q, Wright, E.T, Wu, W, Zhang, C, Vago, F, Ren, Y, Jakata, J, Chiu, W, Serwer, P, Jiang, W.
登録日2014-08-12
公開日2014-10-15
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions.
Proc.Natl.Acad.Sci.USA, 111, 2014
7M3G
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BU of 7m3g by Molmil
Asymmetric Activation of the Calcium Sensing Receptor Homodimer
分子名称: 2-[4-[(3S)-3-[[(1R)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]ethanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G.
登録日2021-03-18
公開日2021-06-30
最終更新日2021-07-21
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Asymmetric activation of the calcium-sensing receptor homodimer.
Nature, 595, 2021
7M3J
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Asymmetric Activation of the Calcium Sensing Receptor Homodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile, ...
著者Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G.
登録日2021-03-18
公開日2021-06-30
最終更新日2021-07-21
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Asymmetric activation of the calcium-sensing receptor homodimer.
Nature, 595, 2021
7M3E
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BU of 7m3e by Molmil
Asymmetric Activation of the Calcium Sensing Receptor Homodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile, ...
著者Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G.
登録日2021-03-18
公開日2021-06-30
最終更新日2021-07-21
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Asymmetric activation of the calcium-sensing receptor homodimer.
Nature, 595, 2021
7M3F
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BU of 7m3f by Molmil
Asymmetric Activation of the Calcium Sensing Receptor Homodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G.
登録日2021-03-18
公開日2021-06-30
最終更新日2021-07-21
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Asymmetric activation of the calcium-sensing receptor homodimer.
Nature, 595, 2021
7JVR
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BU of 7jvr by Molmil
Cryo-EM structure of Bromocriptine-bound dopamine receptor 2 in complex with Gi protein
分子名称: Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E.
登録日2020-08-22
公開日2021-02-24
最終更新日2021-03-31
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
7N9E
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Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB34
分子名称: Nb34 nanobody, Spike glycoprotein
著者Sun, D, Zhang, C, Shi, Y.
登録日2021-06-17
公開日2021-08-04
最終更新日2021-08-11
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
7N9B
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BU of 7n9b by Molmil
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB21
分子名称: NB21 Nanobody, Spike glycoprotein
著者Sun, D, Zhang, C, Shi, Y.
登録日2021-06-17
公開日2021-08-04
最終更新日2021-08-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
7NA8
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BU of 7na8 by Molmil
Structures of human ghrelin receptor-Gi complexes with ghrelin and a synthetic agonist
分子名称: 1-(methanesulfonyl)-1'-(2-methyl-L-alanyl-O-benzyl-D-seryl)-1,2-dihydrospiro[indole-3,4'-piperidine], Antibody fragment, CHOLESTEROL, ...
著者Liu, H, Sun, D, Sun, J, Zhang, C.
登録日2021-06-20
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren
Nat Commun, 12, 2021
7NA7
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BU of 7na7 by Molmil
Structures of human ghrelin receptor-Gi complexes with ghrelin and a synthetic agonist
分子名称: Antibody fragment, CHOLESTEROL, Ghrelin-27, ...
著者Liu, H, Sun, D, Sun, J, Zhang, C.
登録日2021-06-20
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren
Nat Commun, 12, 2021
7N9A
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BU of 7n9a by Molmil
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS RBD with NB21
分子名称: Nanobody Nb21, Spike protein S1
著者Sun, D, Zhang, C, Shi, Y.
登録日2021-06-17
公開日2021-08-04
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes
To Be Published
7N9C
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BU of 7n9c by Molmil
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB95
分子名称: Nanobody NB95, Spike glycoprotein
著者Sun, D, Zhang, C, Shi, Y.
登録日2021-06-17
公開日2021-08-04
最終更新日2021-08-11
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
7NC0
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BU of 7nc0 by Molmil
The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer
分子名称: A33 Fab heavy chain, A33 Fab light chain
著者Tang, J, Zhang, C, Dalby, P, Kozielski, F.
登録日2021-01-28
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer
To Be Published
7NFA
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BU of 7nfa by Molmil
The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer
分子名称: A33 Fab heavy chain, A33 Fab light chain
著者Tang, J, Zhang, C, Dalby, P, Kozielski, F.
登録日2021-02-05
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer
To Be Published
7JVQ
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BU of 7jvq by Molmil
Cryo-EM structure of apomorphine-bound dopamine receptor 1 in complex with Gs protein
分子名称: (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol, CHOLESTEROL, D(1A) dopamine receptor, ...
著者Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E.
登録日2020-08-22
公開日2021-02-24
最終更新日2021-03-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
7JVP
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BU of 7jvp by Molmil
Cryo-EM structure of SKF-83959-bound dopamine receptor 1 in complex with Gs protein
分子名称: (1R)-6-chloro-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, CHOLESTEROL, D(1A) dopamine receptor, ...
著者Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E.
登録日2020-08-22
公開日2021-02-24
最終更新日2021-03-03
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021

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件を2024-06-26に公開中

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