4QKX

Structure of beta2 adrenoceptor bound to a covalent agonist and an engineered nanobody

Summary for 4QKX

Entry DOI	10.2210/pdb4qkx/pdb
Descriptor	Beta-2 adrenergic receptor, R9 protein, SODIUM ION, ... (4 entities in total)
Functional Keywords	7-transmembrane helices, signal transduction, g proteins, membrane, membrane protein-immune system complex, membrane protein/immune system
Biological source	Enterobacteria phage T4 More
Cellular location	Cell membrane ; Multi- pass membrane protein : P07550
Total number of polymer chains	2
Total formula weight	66810.86
Authors	Weichert, D.,Kruse, A.C.,Manglik, A.,Hiller, C.,Zhang, C.,Huebner, H.,Kobilka, B.K.,Gmeiner, P. (deposition date: 2014-06-10, release date: 2014-07-23, Last modification date: 2017-06-28)
Primary citation	Weichert, D.,Kruse, A.C.,Manglik, A.,Hiller, C.,Zhang, C.,Hubner, H.,Kobilka, B.K.,Gmeiner, P. Covalent agonists for studying G protein-coupled receptor activation. Proc.Natl.Acad.Sci.USA, 111:10744-10748, 2014 Cited by PubMed: 25006259 DOI: 10.1073/pnas.1410415111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation