7N9C

Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB95

Summary for 7N9C

• Entry DOI: 10.2210/pdb7n9c/pdb
• EMDB information: 24256
• Descriptor: Spike glycoprotein, Nanobody NB95 (2 entities in total)
• Functional Keywords: covs nb21 nanobody, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2, COVID-19 virus); More
• Total number of polymer chains: 5
• Total formula weight: 491231.85

Authors

Sun, D.,Zhang, C.,Shi, Y. (deposition date: 2021-06-17, release date: 2021-08-04, Last modification date: 2024-10-23)

• Primary citation: Sun, D.,Sang, Z.,Kim, Y.J.,Xiang, Y.,Cohen, T.,Belford, A.K.,Huet, A.,Conway, J.F.,Sun, J.,Taylor, D.J.,Schneidman-Duhovny, D.,Zhang, C.,Huang, W.,Shi, Y.; Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes; Nat Commun, 12:4676-, 2021; DOI: 10.1038/s41467-021-24963-3

Experimental method

ELECTRON MICROSCOPY (3.71 Å)