7NFA

The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer

Summary for 7NFA

• Entry DOI: 10.2210/pdb7nfa/pdb
• Related: 7NC0
• Descriptor: A33 Fab light chain, A33 Fab heavy chain (3 entities in total)
• Functional Keywords: monoclonal antibodies, human a33 fab, colorectal cancer therapy, humanised fab, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 4
• Total formula weight: 94881.98

Authors

Tang, J.,Zhang, C.,Dalby, P.,Kozielski, F. (deposition date: 2021-02-05, release date: 2022-03-02, Last modification date: 2024-01-31)

• Primary citation: Tang, J.,Zhang, C.,Dalby, P.,Kozielski, F.; The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)