7NA7
Structures of human ghrelin receptor-Gi complexes with ghrelin and a synthetic agonist
Summary for 7NA7
Entry DOI | 10.2210/pdb7na7/pdb |
EMDB information | 24267 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | gpcr, appetite, energy homeostasis, reward signaling, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 155593.77 |
Authors | |
Primary citation | Liu, H.,Sun, D.,Myasnikov, A.,Damian, M.,Baneres, J.L.,Sun, J.,Zhang, C. Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren Nat Commun, 12:6410-, 2021 Cited by DOI: 10.1038/s41467-021-26735-5PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
Download full validation report