2QG1
| Crystal structure of the 11th PDZ domain of MPDZ (MUPP1) | Descriptor: | 1,2-ETHANEDIOL, Multiple PDZ domain protein | Authors: | Papagrigoriou, E, Salah, E, Phillips, C, Savitsky, P, Boisguerin, P, Oschkinat, H, Gileadi, C, Yang, X, Elkins, J.M, Ugochukwu, E, Bunkoczi, G, Uppenberg, J, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC) | Deposit date: | 2007-06-28 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of the 11th PDZ domain of MPDZ (MUPP1). To be Published
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6VOC
| icosahedral symmetry reconstruction of brome mosaic virus (RNA 3+4) | Descriptor: | Capsid protein | Authors: | Beren, C, Cui, Y.X, Chakravarty, A, Yang, X, Rao, A.L.N, Knobler, C.M, Zhou, Z.H, Gelbart, W.M. | Deposit date: | 2020-01-30 | Release date: | 2020-05-20 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Genome organization and interaction with capsid protein in a multipartite RNA virus. Proc.Natl.Acad.Sci.USA, 117, 2020
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1NOQ
| e-motif structure | Descriptor: | 5'-D(*CP*CP*GP*CP*CP*G)-3' | Authors: | Zheng, M, Huang, X, Smith, G.K, Yang, X, Gao, X. | Deposit date: | 2003-01-16 | Release date: | 2003-02-11 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Genetically unstable CXG repeats are structurally dynamic and have a high propensity for folding.
An NMR and UV spectroscopic study. J.Mol.Biol., 264, 1996
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3HY0
| Crystal Structure of catalytic fragment of E. coli AlaRS G237A in complex with GlySA | Descriptor: | 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-(glycylsulfamoyl)adenosine, ... | Authors: | Guo, M, Yang, X.-L, Schimmel, P. | Deposit date: | 2009-06-22 | Release date: | 2009-12-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma. Nature, 462, 2009
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3HXX
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3HXW
| Crystal Structure of catalytic fragment of E. coli AlaRS in complex with SerSA | Descriptor: | 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, ... | Authors: | Guo, M, Yang, X.-L, Schimmel, P. | Deposit date: | 2009-06-22 | Release date: | 2009-12-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma. Nature, 462, 2009
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3HXU
| Crystal Structure of catalytic fragment of E. coli AlaRS in complex with AlaSA | Descriptor: | '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Guo, M, Yang, X.-L, Schimmel, P. | Deposit date: | 2009-06-22 | Release date: | 2009-12-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma. Nature, 462, 2009
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3HXY
| Crystal Structure of catalytic fragment of E. coli AlaRS in complex with AMPPCP, Ala-AMP and PCP | Descriptor: | 2-HYDROXYETHYL DISULFIDE, 5'-O-[(R)-{[(2S)-2-aminopropanoyl]oxy}(hydroxy)phosphoryl]adenosine, Alanyl-tRNA synthetase, ... | Authors: | Guo, M, Yang, X.-L, Schimmel, P. | Deposit date: | 2009-06-22 | Release date: | 2009-12-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma. Nature, 462, 2009
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3HXV
| Crystal Structure of catalytic fragment of E. coli AlaRS in complex with GlySA | Descriptor: | 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-(glycylsulfamoyl)adenosine, ... | Authors: | Guo, M, Yang, X.-L, Schimmel, P. | Deposit date: | 2009-06-22 | Release date: | 2009-12-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma. Nature, 462, 2009
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3HY1
| Crystal Structure of catalytic fragment of E. coli AlaRS G237A in complex with SerSA | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-HYDROXYETHYL DISULFIDE, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, ... | Authors: | Guo, M, Yang, X.-L, Schimmel, P. | Deposit date: | 2009-06-22 | Release date: | 2009-12-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma. Nature, 462, 2009
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6PZT
| cryo-EM structure of human NKCC1 | Descriptor: | Solute carrier family 12 member 2 | Authors: | Cao, E, Wang, Q, Yang, X. | Deposit date: | 2019-08-01 | Release date: | 2020-03-25 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structure of the human cation-chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy. Nat Commun, 11, 2020
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6EO6
| X-ray structure of the complex between human alpha-thrombin and modified 15-mer DNA aptamer containing 5-(3-(2-(1H-indol-3-yl)acetamide-N-yl)-1-propen-1-yl)-2'-deoxyuridine residue | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, GA63A - TBA MODIFIED APTAMER, ... | Authors: | Dolot, R.M, Nawrot, B, Yang, X. | Deposit date: | 2017-10-09 | Release date: | 2017-10-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity. Nucleic Acids Res., 46, 2018
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6EO7
| X-ray structure of the complex between human alpha-thrombin and modified 15-mer DNA aptamer containing 5-(3-(acetamide-N-yl)-1-propen-1-yl)-2'-deoxyuridine residue | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, GA68B2 - MODIFIED HUMAN THROMBIN BINDING APTAMER, ... | Authors: | Dolot, R.M, Nawrot, B, Yang, X. | Deposit date: | 2017-10-09 | Release date: | 2017-10-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity. Nucleic Acids Res., 46, 2018
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8DQL
| CryoEM structure of IglD | Descriptor: | Secretion system protein | Authors: | Liu, X, Clemens, D, Lee, B, Yang, X, Zhou, H, Horwitz, M. | Deposit date: | 2022-07-19 | Release date: | 2022-08-17 | Last modified: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Atomic Structure of IglD Demonstrates Its Role as a Component of the Baseplate Complex of the Francisella Type VI Secretion System. Mbio, 13, 2022
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6AJH
| Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with AU1235 | Descriptor: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 1-(2-adamantyl)-3-[2,3,4-tris(fluoranyl)phenyl]urea, Drug exporters of the RND superfamily-like protein,Endolysin, ... | Authors: | Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H. | Deposit date: | 2018-08-27 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.818 Å) | Cite: | Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176, 2019
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6AJI
| Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with Rimonabant | Descriptor: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide, Drug exporters of the RND superfamily-like protein,Endolysin, ... | Authors: | Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H. | Deposit date: | 2018-08-27 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176, 2019
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6AJF
| Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis | Descriptor: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Drug exporters of the RND superfamily-like protein,Endolysin, alpha-D-glucopyranosyl 6-O-dodecyl-alpha-D-glucopyranoside | Authors: | Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H. | Deposit date: | 2018-08-27 | Release date: | 2018-12-26 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.698 Å) | Cite: | Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176, 2019
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6AJG
| Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with SQ109 | Descriptor: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, DODECYL-BETA-D-MALTOSIDE, Drug exporters of the RND superfamily-like protein,Endolysin, ... | Authors: | Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H. | Deposit date: | 2018-08-27 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176, 2019
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6AJJ
| Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with ICA38 | Descriptor: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 4,6-difluoro-N-(spiro[5.5]undecan-3-yl)-1H-indole-2-carboxamide, Drug exporters of the RND superfamily-like protein,Endolysin, ... | Authors: | Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H. | Deposit date: | 2018-08-27 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.794 Å) | Cite: | Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176, 2019
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3HXZ
| Crystal Structure of catalytic fragment of E. coli AlaRS G237A in complex with AlaSA | Descriptor: | '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Guo, M, Yang, X.-L, Schimmel, P. | Deposit date: | 2009-06-22 | Release date: | 2009-12-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma. Nature, 462, 2009
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3UIT
| Overall structure of Patj/Pals1/Mals complex | Descriptor: | ACETATE ION, InaD-like protein, MAGUK p55 subfamily member 5, ... | Authors: | Zhang, J, Yang, X, Long, J, Shen, Y. | Deposit date: | 2011-11-06 | Release date: | 2012-02-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of an L27 domain heterotrimer from cell polarity complex Patj/Pals1/Mals2 reveals mutually independent L27 domain assembly mode J.Biol.Chem., 287, 2012
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2C2H
| CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP | Descriptor: | CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Debreczeni, J.E, Yang, X, Zao, Y, Elkins, J, Gileadi, C, Burgess, N, Colebrook, S, Gileadi, O, Fedorov, O, Bunkoczi, G, von Delft, F, Doyle, D, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A. | Deposit date: | 2005-09-29 | Release date: | 2005-10-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structure of the Human Rac3 in Complex with Gdp To be Published
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1NBS
| Crystal structure of the specificity domain of Ribonuclease P RNA | Descriptor: | LEAD (II) ION, MAGNESIUM ION, RIBONUCLEASE P RNA | Authors: | Krasilnikov, A.S, Yang, X, Pan, T, Mondragon, A. | Deposit date: | 2002-12-03 | Release date: | 2003-02-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Crystal structure of the specificity domain of Ribonuclease P Nature, 421, 2003
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5G06
| Cryo-EM structure of yeast cytoplasmic exosome | Descriptor: | EXOSOME COMPLEX COMPONENT CSL4, EXOSOME COMPLEX COMPONENT MTR3, EXOSOME COMPLEX COMPONENT RRP4, ... | Authors: | Liu, J.J, Niu, C.Y, Wu, Y, Tan, D, Wang, Y, Ye, M.D, Liu, Y, Zhao, W.W, Zhou, K, Liu, Q.S, Dai, J.B, Yang, X.R, Dong, M.Q, Huang, N, Wang, H.W. | Deposit date: | 2016-03-17 | Release date: | 2016-06-15 | Last modified: | 2017-08-02 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryoem Structure of Yeast Cytoplasmic Exosome Complex. Cell Res., 26, 2016
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2C23
| 14-3-3 Protein Beta (Human) in complex with exoenzyme S peptide | Descriptor: | 14-3-3 BETA/ALPHA, EXOENZYME S PEPTIDE | Authors: | Elkins, J.M, Schoch, G.A, Yang, X, Sundstrom, M, Arrowsmith, C, Edwards, A, Doyle, D.A. | Deposit date: | 2005-09-26 | Release date: | 2005-09-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family. Proc.Natl.Acad.Sci.USA, 103, 2006
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