Crystal Structure of catalytic fragment of E. coli AlaRS in complex with GlySA

Summary for 3HXV

Related3HXU 3HXW 3HXX 3HXY 3HXZ 3HY0 3HY1
DescriptorAlanyl-tRNA synthetase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 2-HYDROXYETHYL DISULFIDE, ... (6 entities in total)
Functional Keywordsaminoacyl-trna synthetase, ligase, protein biosynthesis, nucleotide-binding, amino acid-binding, atp-binding, metal-binding, zinc-finger
Biological sourceEscherichia coli
Cellular locationCytoplasm P00957
Total number of polymer chains1
Total molecular weight51106.62
Guo, M.,Yang, X.-L.,Schimmel, P. (deposition date: 2009-06-22, release date: 2009-12-15, Last modification date: 2017-11-01)
Primary citation
Guo, M.,Chong, Y.E.,Shapiro, R.,Beebe, K.,Yang, X.L.,Schimmel, P.
Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462:808-812, 2009
PubMed: 20010690 (PDB entries with the same primary citation)
DOI: 10.1038/nature08612
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.186300.5%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3hxv
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Molmil generated image of 3hxv
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Molmil generated image of 3hxv
rotated about y axis by 90°