3HXW

Crystal Structure of catalytic fragment of E. coli AlaRS in complex with SerSA

Summary for 3HXW

Entry DOI	10.2210/pdb3hxw/pdb
Related	3HXU 3HXV 3HXX 3HXY 3HXZ 3HY0 3HY1
Descriptor	Alanyl-tRNA synthetase, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total)
Functional Keywords	aminoacyl-trna synthetase, ligase, protein biosynthesis, nucleotide-binding, amino acid-binding, atp-binding, metal-binding, zinc-finger
Biological source	Escherichia coli
Cellular location	Cytoplasm: P00957
Total number of polymer chains	1
Total formula weight	51058.51
Authors	Guo, M.,Yang, X.-L.,Schimmel, P. (deposition date: 2009-06-22, release date: 2009-12-15, Last modification date: 2024-02-21)
Primary citation	Guo, M.,Chong, Y.E.,Shapiro, R.,Beebe, K.,Yang, X.L.,Schimmel, P. Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma. Nature, 462:808-812, 2009 Cited by PubMed: 20010690 DOI: 10.1038/nature08612 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.93 Å)

Structure validation