6AJJ

Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with ICA38

Summary for 6AJJ

Entry DOI	10.2210/pdb6ajj/pdb
Descriptor	Drug exporters of the RND superfamily-like protein,Endolysin, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, alpha-D-glucopyranosyl 6-O-dodecyl-alpha-D-glucopyranoside, ... (4 entities in total)
Functional Keywords	membrane protein, transporter, rnd family, cell wall biosynthesis, drug target, hydrolase
Biological source	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) More
Total number of polymer chains	1
Total formula weight	107287.43
Authors	Zhang, B.,Li, J.,Yang, X.L.,Wu, L.J.,Yang, H.T.,Rao, Z.H. (deposition date: 2018-08-27, release date: 2018-12-26, Last modification date: 2023-11-22)
Primary citation	Zhang, B.,Li, J.,Yang, X.,Wu, L.,Zhang, J.,Yang, Y.,Zhao, Y.,Zhang, L.,Yang, X.,Yang, X.,Cheng, X.,Liu, Z.,Jiang, B.,Jiang, H.,Guddat, L.W.,Yang, H.,Rao, Z. Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176:636-648.e13, 2019 Cited by PubMed: 30682372 DOI: 10.1016/j.cell.2019.01.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.794 Å)

Structure validation