6AJH
Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with AU1235
Summary for 6AJH
Entry DOI | 10.2210/pdb6ajh/pdb |
Descriptor | Drug exporters of the RND superfamily-like protein,Endolysin, 1-(2-adamantyl)-3-[2,3,4-tris(fluoranyl)phenyl]urea, alpha-D-glucopyranosyl 6-O-dodecyl-alpha-D-glucopyranoside, ... (4 entities in total) |
Functional Keywords | membrane protein, transporter, rnd family, cell wall biosynthesis, drug target, hydrolase |
Biological source | Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) More |
Total number of polymer chains | 1 |
Total formula weight | 107455.51 |
Authors | Zhang, B.,Li, J.,Yang, X.L.,Wu, L.J.,Yang, H.T.,Rao, Z.H. (deposition date: 2018-08-27, release date: 2018-12-26, Last modification date: 2023-11-22) |
Primary citation | Zhang, B.,Li, J.,Yang, X.,Wu, L.,Zhang, J.,Yang, Y.,Zhao, Y.,Zhang, L.,Yang, X.,Yang, X.,Cheng, X.,Liu, Z.,Jiang, B.,Jiang, H.,Guddat, L.W.,Yang, H.,Rao, Z. Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176:636-648.e13, 2019 Cited by PubMed: 30682372DOI: 10.1016/j.cell.2019.01.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.818 Å) |
Structure validation
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