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PDB: 786 results

6LNB
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CryoEM structure of Cascade-TniQ-dsDNA complex
Descriptor: CRISPR RNA (60-MER), CRISPR-associated protein Cas6, CRISPR-associated protein Cas7, ...
Authors:Wang, B, Xu, W, Yang, H.
Deposit date:2019-12-28
Release date:2020-02-19
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structural basis of a Tn7-like transposase recruitment and DNA loading to CRISPR-Cas surveillance complex.
Cell Res., 30, 2020
5WBH
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Structure of the FRB domain of mTOR bound to a substrate recruitment peptide of S6K1
Descriptor: Ribosomal protein S6 kinase beta-1, Serine/threonine-protein kinase mTOR
Authors:Pavletich, N.P, Yang, H.
Deposit date:2017-06-29
Release date:2017-12-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
8YFJ
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TRIP4 ASCH domain in complex with a 12bp dsDNA (5'-ATTGGATCCAAT-3')
Descriptor: Activating signal cointegrator 1, DNA (5'-D(*AP*TP*TP*GP*GP*AP*TP*CP*CP*AP*AP*T)-3')
Authors:Ding, J, Yang, H, Hu, C.
Deposit date:2024-02-24
Release date:2024-06-26
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role.
Structure, 32, 2024
8YEY
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TRIP4 ASCH domain in complex with ssDNA-1
Descriptor: Activating signal cointegrator 1, DNA (5'-D(*GP*TP*TP*TP*C)-3')
Authors:Ding, J, Yang, H, Hu, C.
Deposit date:2024-02-23
Release date:2024-06-26
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role.
Structure, 32, 2024
8YFI
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TRIP4 ASCH domain in complex with a 12bp dsDNA (5'-TGAGGTACCTCA-3')
Descriptor: Activating signal cointegrator 1, DNA (5'-D(*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*CP*A)-3')
Authors:Ding, J, Yang, H, Hu, C.
Deposit date:2024-02-24
Release date:2024-06-26
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role.
Structure, 32, 2024
8YEW
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TRIP4 ASCH domain in unliganded form
Descriptor: Activating signal cointegrator 1
Authors:Ding, J, Yang, H, Hu, C.
Deposit date:2024-02-23
Release date:2024-06-26
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role.
Structure, 32, 2024
8YXX
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TRIP4 ASCH domain in complex with a 12bp dsDNA (5'-TGAGGTACCTCG-3')
Descriptor: Activating signal cointegrator 1, DNA (5'-D(*CP*GP*AP*GP*GP*TP*AP*CP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*CP*G)-3')
Authors:Ding, J, Yang, H, Hu, C.
Deposit date:2024-04-03
Release date:2024-06-26
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role.
Structure, 32, 2024
8YXW
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TRIP4 ASCH domain in complex with a 12bp dsDNA (5'-TGAGGTACCTCC-3')
Descriptor: Activating signal cointegrator 1, DNA (5'-D(*GP*GP*AP*GP*GP*TP*AP*CP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*CP*C)-3')
Authors:Ding, J, Yang, H, Hu, C.
Deposit date:2024-04-03
Release date:2024-06-26
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role.
Structure, 32, 2024
5C56
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Crystal structure of USP7/HAUSP in complex with ICP0
Descriptor: Ubiquitin E3 ligase ICP0, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Cheng, J, Li, Z, Gong, R, Fang, J, Yang, Y, Sun, C, Yang, H, Xu, Y.
Deposit date:2015-06-19
Release date:2015-07-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.685 Å)
Cite:Molecular mechanism for the substrate recognition of USP7.
Protein Cell, 6, 2015
3IU3
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BU of 3iu3 by Molmil
Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain
Descriptor: Heavy chain of Fab fragment of Basiliximab, Interleukin-2 receptor alpha chain, Light chain of Fab fragment of Basiliximab, ...
Authors:Du, J, Yang, H, Wang, J, Ding, J.
Deposit date:2009-08-29
Release date:2010-01-26
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for the blockage of IL-2 signaling by therapeutic antibody basiliximab
J.Immunol., 184, 2010
4UBD
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BU of 4ubd by Molmil
Crystal structure of a neutralizing human monoclonal antibody with 1968 H3 HA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Shore, D.A, Yang, H, Cho, M, Donis, R.O, Stevens, J.
Deposit date:2014-08-12
Release date:2015-06-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus.
Nat Commun, 6, 2015
5EU8
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Structure of FIPV main protease in complex with dual inhibitors
Descriptor: 1,2-ETHANEDIOL, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE, ZINC ION, ...
Authors:Wang, F, Chen, C, Liu, X, Yang, K, Xu, X, Yang, H.
Deposit date:2015-11-18
Release date:2015-12-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.447 Å)
Cite:Crystal Structure of Feline Infectious Peritonitis Virus Main Protease in Complex with Synergetic Dual Inhibitors
J.Virol., 90, 2015
5U77
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BU of 5u77 by Molmil
Crystal structure of ORP8 PH domain
Descriptor: FORMIC ACID, N-(2-hydroxyethyl)-N,N-dimethyl-3-sulfopropan-1-aminium, Oxysterol-binding protein-related protein 8
Authors:Ghai, R, Yang, H.
Deposit date:2016-12-11
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.157 Å)
Cite:ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane.
Nat Commun, 8, 2017
4ZWJ
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BU of 4zwj by Molmil
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
Descriptor: Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin
Authors:Kang, Y, Zhou, X.E, Gao, X, He, Y, Liu, W, Ishchenko, A, Barty, A, White, T.A, Yefanov, O, Han, G.W, Xu, Q, de Waal, P.W, Ke, J, Tan, M.H.E, Zhang, C, Moeller, A, West, G.M, Pascal, B, Eps, N.V, Caro, L.N, Vishnivetskiy, S.A, Lee, R.J, Suino-Powell, K.M, Gu, X, Pal, K, Ma, J, Zhi, X, Boutet, S, Williams, G.J, Messerschmidt, M, Gati, C, Zatsepin, N.A, Wang, D, James, D, Basu, S, Roy-Chowdhury, S, Conrad, C, Coe, J, Liu, H, Lisova, S, Kupitz, C, Grotjohann, I, Fromme, R, Jiang, Y, Tan, M, Yang, H, Li, J, Wang, M, Zheng, Z, Li, D, Howe, N, Zhao, Y, Standfuss, J, Diederichs, K, Dong, Y, Potter, C.S, Carragher, B, Caffrey, M, Jiang, H, Chapman, H.N, Spence, J.C.H, Fromme, P, Weierstall, U, Ernst, O.P, Katritch, V, Gurevich, V.V, Griffin, P.R, Hubbell, W.L, Stevens, R.C, Cherezov, V, Melcher, K, Xu, H.E, GPCR Network (GPCR)
Deposit date:2015-05-19
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.302 Å)
Cite:Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
Nature, 523, 2015
3CXD
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BU of 3cxd by Molmil
Crystal structure of anti-osteopontin antibody 23C3 in complex with its epitope peptide
Descriptor: Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ...
Authors:Du, J, Yang, H, Zhong, C, Ding, J.
Deposit date:2008-04-24
Release date:2008-10-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis
J.Mol.Biol., 382, 2008
1NH9
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BU of 1nh9 by Molmil
Crystal Structure of a DNA Binding Protein Mja10b from the hyperthermophile Methanococcus jannaschii
Descriptor: DNA-binding protein Alba
Authors:Wang, G, Bartlam, M, Guo, R, Yang, H, Xue, H, Liu, Y, Huang, L, Rao, Z.
Deposit date:2002-12-19
Release date:2003-12-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a DNA binding protein from the hyperthermophilic euryarchaeon Methanococcus jannaschii
Protein Sci., 12, 2003
3DSF
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BU of 3dsf by Molmil
Crystal structure of anti-osteopontin antibody 23C3 in complex with W43A mutated epitope peptide
Descriptor: Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ...
Authors:Du, J, Zhong, C, Yang, H, Ding, J.
Deposit date:2008-07-12
Release date:2008-10-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis
J.Mol.Biol., 382, 2008
1LBY
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Crystal Structure of a complex (P32 crystal form) of dual activity FBPase/IMPase (AF2372) from Archaeoglobus fulgidus with 3 Manganese ions, Fructose-6-Phosphate, and Phosphate ion
Descriptor: 6-O-phosphono-beta-D-fructofuranose, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Stieglitz, K.A, Johnson, K.A, Yang, H, Roberts, M.F, Seaton, B.A, Head, J.F, Stec, B.
Deposit date:2002-04-04
Release date:2002-05-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of a dual activity IMPase/FBPase (AF2372) from Archaeoglobus fulgidus. The story of a mobile loop.
J.Biol.Chem., 277, 2002
5U78
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BU of 5u78 by Molmil
Crystal structure of ORP8 PH domain in P1211 space group
Descriptor: Oxysterol-binding protein-related protein 8
Authors:Ghai, R, Yang, H.
Deposit date:2016-12-12
Release date:2017-10-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.978 Å)
Cite:ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane.
Nat Commun, 8, 2017
1LBV
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BU of 1lbv by Molmil
Crystal Structure of apo-form (P21) of dual activity FBPase/IMPase (AF2372) from Archaeoglobus fulgidus
Descriptor: fructose 1,6-bisphosphatase/inositol monophosphatase
Authors:Stieglitz, K.A, Johnson, K.A, Yang, H, Roberts, M.F, Seaton, B.A, Head, J.F, Stec, B.
Deposit date:2002-04-04
Release date:2002-05-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a dual activity IMPase/FBPase (AF2372) from Archaeoglobus fulgidus. The story of a mobile loop.
J.Biol.Chem., 277, 2002
1LBW
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BU of 1lbw by Molmil
Crystal Structure of apo-form (P32) of dual activity FBPase/IMPase (AF2372) from Archaeoglobus fulgidus
Descriptor: fructose 1,6-bisphosphatase/inositol monophosphatase
Authors:Stieglitz, K.A, Johnson, K.A, Yang, H, Roberts, M.F, Seaton, B.A, Head, J.F, Stec, B.
Deposit date:2002-04-04
Release date:2002-05-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a dual activity IMPase/FBPase (AF2372) from Archaeoglobus fulgidus. The story of a mobile loop.
J.Biol.Chem., 277, 2002
1LBZ
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BU of 1lbz by Molmil
Crystal Structure of a complex (P32 crystal form) of dual activity FBPase/IMPase (AF2372) from Archaeoglobus fulgidus with 3 Calcium ions and Fructose-1,6 bisphosphate
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, CALCIUM ION, fructose 1,6-bisphosphatase/inositol monophosphatase
Authors:Stieglitz, K.A, Johnson, K.A, Yang, H, Roberts, M.F, Seaton, B.A, Head, J.F, Stec, B.
Deposit date:2002-04-04
Release date:2002-05-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a dual activity IMPase/FBPase (AF2372) from Archaeoglobus fulgidus. The story of a mobile loop.
J.Biol.Chem., 277, 2002
1LBX
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Crystal Structure of a ternary complex of dual activity FBPase/IMPase (AF2372) from Archaeoglobus fulgidus with Calcium ions and D-myo-Inositol-1-Phosphate
Descriptor: CALCIUM ION, D-MYO-INOSITOL-1-PHOSPHATE, fructose 1,6-bisphosphatase/inositol monophosphatase
Authors:Stieglitz, K.A, Johnson, K.A, Yang, H, Roberts, M.F, Seaton, B.A, Head, J.F, Stec, B.
Deposit date:2002-04-04
Release date:2002-05-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a dual activity IMPase/FBPase (AF2372) from Archaeoglobus fulgidus. The story of a mobile loop.
J.Biol.Chem., 277, 2002
7A5K
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BU of 7a5k by Molmil
Structure of the human mitoribosome in the post translocation state bound to mtEF-G1
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ...
Authors:Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V.
Deposit date:2020-08-21
Release date:2020-12-23
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Elongational stalling activates mitoribosome-associated quality control.
Science, 370, 2020
6BCX
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mTORC1 structure refined to 3.0 angstroms
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-binding protein 1, MAGNESIUM ION, ...
Authors:Pavletich, N.P, Yang, H.
Deposit date:2017-10-20
Release date:2017-12-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017

226707

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