9KR6

Cryo-EM structure of MPXV core protease in complex with the substrate derivative I-G18

Summary for 9KR6

• Entry DOI: 10.2210/pdb9kr6/pdb
• EMDB information: 62520
• Descriptor: Core protease I7, Core protein VP8 (2 entities in total)
• Functional Keywords: orthopoxviruses, monkeypox, protease, viral replication, drug discovery, viral protein
• Biological source: Monkeypox virus; More
• Total number of polymer chains: 4
• Total formula weight: 100431.44

Authors

Lan, W.,You, T.,Li, D.,Dong, X.,Wang, H.,Xu, J.,Wang, W.,Gao, Y.,Yang, H. (deposition date: 2024-11-27, release date: 2025-03-12, Last modification date: 2025-03-26)

• Primary citation: Lan, W.,You, T.,Li, D.,Dong, X.,Wang, H.,Xu, J.,Wang, W.,Gao, Y.,Yang, H.; Cryo-Em Structure Of Mpox Core Protease In Complex With The Substrate Analogue I-G18; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.8 Å)